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来自植物的生物活性抗菌肽。

Biologically active and antimicrobial peptides from plants.

作者信息

Salas Carlos E, Badillo-Corona Jesus A, Ramírez-Sotelo Guadalupe, Oliver-Salvador Carmen

机构信息

Departamento de Bioquímica, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, Brazil.

Unidad Profesional Interdisciplinaria de Biotecnología, Instituto Politécnico Nacional, Avenida Acueducto S/N, Colonia Barrio La Laguna Ticomán, 07320 Mexico City, Mexico.

出版信息

Biomed Res Int. 2015;2015:102129. doi: 10.1155/2015/102129. Epub 2015 Mar 1.

Abstract

Bioactive peptides are part of an innate response elicited by most living forms. In plants, they are produced ubiquitously in roots, seeds, flowers, stems, and leaves, highlighting their physiological importance. While most of the bioactive peptides produced in plants possess microbicide properties, there is evidence that they are also involved in cellular signaling. Structurally, there is an overall similarity when comparing them with those derived from animal or insect sources. The biological action of bioactive peptides initiates with the binding to the target membrane followed in most cases by membrane permeabilization and rupture. Here we present an overview of what is currently known about bioactive peptides from plants, focusing on their antimicrobial activity and their role in the plant signaling network and offering perspectives on their potential application.

摘要

生物活性肽是大多数生命形式引发的先天反应的一部分。在植物中,它们在根、种子、花、茎和叶中普遍产生,突出了它们的生理重要性。虽然植物中产生的大多数生物活性肽具有杀微生物特性,但有证据表明它们也参与细胞信号传导。在结构上,将它们与来自动物或昆虫来源的生物活性肽进行比较时,存在总体相似性。生物活性肽的生物作用始于与靶膜的结合,在大多数情况下随后是膜通透性增加和破裂。在此,我们概述了目前对植物生物活性肽的了解,重点关注它们的抗菌活性及其在植物信号网络中的作用,并对其潜在应用提出展望。

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