State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Mailbox No. 75, Science and Technology, No. 15 North Third Ring East Road, Chaoyang District, Beijing 100029, PR China.
State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Mailbox No. 75, Science and Technology, No. 15 North Third Ring East Road, Chaoyang District, Beijing 100029, PR China.
Carbohydr Polym. 2015 May 20;122:5-10. doi: 10.1016/j.carbpol.2015.01.003. Epub 2015 Jan 12.
Sulforaphene (SFE) was extracted from the radish seeds and the purity of SFE extracted by our laboratory was 95%. It is well known that SFE can prevent cancers. It is also known that SFE is unstable to heat. To overcome the problem, SFE microcapsules using natural biopolymers were prepared by spray drying. The results indicated that SFE microcapsules using hydroxypropyl-β-cyclodextrin (HP-β-CD), maltodextrin (MD) and isolated soybean protein (SPI) as wall materials could effectively improve its stability against heat, especially SFE-loaded HP-β-CD and MD microcapsules. The amount of SFE in the microcapsules was found 20% higher than that of the non-encapsulated SFE under 90 °C in 168 h. Our finding suggested that the rate of degradation of the non-encapsulated and encapsulated SFE with HP-β-CD, MD and SPI followed the first-order kinetics. The speed of the degradation of the encapsulated SFE in biopolymers increased from SFE with HP-β-CD, to SFE with MD, and to SFE-SPI. The non-encapsulated SFE degrades fastest.
萝卜硫素（SFE）是从萝卜种子中提取的，本实验室提取的 SFE 纯度为 95%。众所周知，SFE 可以预防癌症。也知道 SFE 对热不稳定。为了克服这个问题，采用喷雾干燥法制备了使用天然生物聚合物的 SFE 微胶囊。结果表明，以羟丙基-β-环糊精（HP-β-CD）、麦芽糊精（MD）和分离大豆蛋白（SPI）为壁材的 SFE 微胶囊可以有效提高其对热的稳定性，特别是 SFE 负载的 HP-β-CD 和 MD 微胶囊。在 90°C 下，168 小时后，微胶囊中 SFE 的含量比未包裹的 SFE 高 20%。我们的发现表明，未包裹和包裹有 HP-β-CD、MD 和 SPI 的 SFE 的降解速率遵循一级动力学。在生物聚合物中，包裹 SFE 的降解速度从 SFE-HP-β-CD 增加到 SFE-MD，再增加到 SFE-SPI。未包裹的 SFE 降解最快。
