Ohno H, Yamashita K, Doi R, Yamamura K, Kondo T, Taniguchi N
J Appl Physiol (1985). 1985 May;58(5):1453-8. doi: 10.1152/jappl.1985.58.5.1453.
Effects of cycle ergometer exercise (approximately 75% maximum ventilatory O2 consumption for 30 min) on the concentrations of zinc and related proteins in erythrocytes and/or plasma were studied on 11 sedentary male students. Lower concentrations of total zinc and of zinc derived from carbonic anhydrase I type (CA-I) in erythrocytes were observed immediately after exercise, but they disappeared after 30 min of rest. The change in total zinc concentration in erythrocytes correlated well with that in CA-I concentration immediately after exercise, as well as after rest. The concentration of carbonic anhydrase II type (CA-II)-derived zinc did not vary substantially at any time. On the other hand, there were significant increases in the plasma concentrations of total zinc and of alpha 2-macroglobulin (alpha 2-MG)-bound zinc immediately after exercise, whereas no such effect was noted in albumin-bound zinc. A positive correlation was found between total zinc and alpha 2-MG concentrations in plasma immediately after exercise. In addition, the change in the activity of alkaline phosphatase, a zinc metalloenzyme, correlated well with that in the total zinc concentration in plasma. These results suggest that a brief physical exercise induces the movement of zinc into plasma.
对11名久坐不动的男学生研究了周期测力计运动（以大约75%的最大通气耗氧量进行30分钟）对红细胞和/或血浆中锌及相关蛋白质浓度的影响。运动后即刻观察到红细胞中总锌以及源自碳酸酐酶I型（CA-I）的锌浓度降低，但休息30分钟后这些降低消失。运动后即刻以及休息后，红细胞中总锌浓度的变化与CA-I浓度的变化密切相关。源自碳酸酐酶II型（CA-II）的锌浓度在任何时候都没有显著变化。另一方面，运动后即刻血浆中总锌以及与α2-巨球蛋白（α2-MG）结合的锌浓度显著升高，而与白蛋白结合的锌未观察到此类效应。运动后即刻血浆中总锌与α2-MG浓度之间呈正相关。此外，锌金属酶碱性磷酸酶的活性变化与血浆中总锌浓度的变化密切相关。这些结果表明，一次短暂的体育锻炼会促使锌向血浆中转移。
