牛支原体的毒力、持续性和传播
Virulence, persistence and dissemination of Mycoplasma bovis.
作者信息
Bürki Sibylle, Frey Joachim, Pilo Paola
机构信息
Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.
Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
出版信息
Vet Microbiol. 2015 Aug 31;179(1-2):15-22. doi: 10.1016/j.vetmic.2015.02.024. Epub 2015 Mar 2.
Bovine mycoplasmosis due to Mycoplasma bovis causes several important bovine diseases such as pneumonia, mastitis, arthritis, otitis, genital disorders or keratoconjunctivitis. Variable surface lipoproteins, adhesion, invasion of host cells, modulation of the host immune system, biofilm formation and the release of secondary metabolites like hydrogen peroxide, as well as synergistic infections with other bacterial or viral pathogens are among the more significantly studied characteristics of the bacterium. The aim of this review is to summarize the current knowledge regarding the virulence of M. bovis and additionally, factors contributing to the dissemination and persistence of this pathogen in the bovine host will be discussed.
由牛支原体引起的牛支原体病会引发多种重要的牛病，如肺炎、乳腺炎、关节炎、中耳炎、生殖系统疾病或角膜结膜炎。可变表面脂蛋白、黏附、宿主细胞侵袭、宿主免疫系统调节、生物膜形成以及过氧化氢等次生代谢产物的释放，还有与其他细菌或病毒病原体的协同感染，都是对该细菌研究得较为深入的特征。本综述的目的是总结关于牛支原体毒力的现有知识，此外，还将讨论促成该病原体在牛宿主中传播和持续存在的因素。
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