McClure Allison W, Lew Daniel J
Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710.
Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710
J Cell Biol. 2015 Mar 30;208(7):867-8. doi: 10.1083/jcb.201502095.
During mating, yeast cells must perforate their rigid cell walls at the right place to allow cell-cell fusion. In this issue, Dudin et al. (2015; J. Cell Biol. http://dx.doi.org/jcb.201411124) image mating fission yeast cells with unprecedented spatiotemporal resolution. The authors find that when mating cells come into contact, they form aster-like actin structures that direct cell wall remodeling precisely to the point of contact.
在交配过程中,酵母细胞必须在正确的位置穿透其坚硬的细胞壁,以实现细胞间融合。在本期杂志中,杜丁等人(2015年;《细胞生物学杂志》,http://dx.doi.org/jcb.201411124)以前所未有的时空分辨率对交配的裂殖酵母细胞进行成像。作者发现,当交配细胞接触时,它们会形成星状肌动蛋白结构,将细胞壁重塑精确地引导到接触点。