Fu Weili, Li Qi, Li Jian
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2014 Dec;28(12):1560-4.
To review the research progress of the preparation and components of the platelet rich plasma (PRP).
The recent literature concerning the biological mechanism, preparation, and components of PRP was analyzed and summarized.
The biological function of PRP depends on a series of intricate cascade of cellular and molecular events. PRP contains different concentrations of platelets, which would release a large number of the activated molecules, and also contains a small amount of white blood cells and red blood cells. The preparation of PRP is based on platelet concentration. Different preparation techniques would lead to different platelet concentrations, recovery ratios, and components.
There is no uniform standard for the preparation of PRP. Different preparation methods and technical parameters of PRP will get different components and different concentrations of PRP, which also provide a reference for clinicians to select the most appropriate PRP for individual patient.
综述富血小板血浆(PRP)的制备及成分研究进展。
分析并总结近期有关PRP生物学机制、制备及成分的文献。
PRP的生物学功能取决于一系列复杂的细胞和分子事件级联反应。PRP含有不同浓度的血小板,这些血小板会释放大量活化分子,还含有少量白细胞和红细胞。PRP的制备基于血小板浓度。不同的制备技术会导致不同的血小板浓度、回收率和成分。
PRP的制备尚无统一标准。PRP不同的制备方法和技术参数会得到不同的成分和不同浓度的PRP,这也为临床医生为个体患者选择最合适的PRP提供了参考。