Lee Ji Ha, Lee Jin Hyeok, Jung Sung Ho, Hyun Tae Kyung, Feng Mingxiao, Kim Jae-Yean, Lee Jae-Hong, Lee Hoyeon, Kim Jong Seung, Kang Chulhun, Kwon Ki-Young, Jung Jong Hwa
Department of Chemistry and Research Institute of Natural Sciences, Gyeongsang National University, Jinju, South Korea.
Chem Commun (Camb). 2015 May 1;51(35):7463-5. doi: 10.1039/c5cc01364j.
2-(N,N-Dimethylamino)naphthalene-based probe 1 was found to exhibit a dramatic enhancement in fluorescence upon addition of Zn(2+), but not with any other metal ions. Probe 1 as a chemoprobe enabled high-resolution fluorescence imaging of zinc ions in HeLa cells and Arabidopsis.
基于2-(N,N-二甲基氨基)萘的探针1在加入Zn(2+)后荧光显著增强,但加入其他任何金属离子时均无此现象。探针1作为一种化学探针能够对HeLa细胞和拟南芥中的锌离子进行高分辨率荧光成像。