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基于吲哚的荧光化学传感器用于检测水相介质和斑马鱼中的 Zn。

An Indole-Based Fluorescent Chemosensor for Detecting Zn in Aqueous Media and Zebrafish.

机构信息

Department of Fine Chem and Renewable Energy Convergence, Seoul National University of Science and Technology (SNUT), Seoul 139-743, Korea.

Department of Environmental Engineering, Seoul National University of Science and Technology (SNUT), Seoul 139-743, Korea.

出版信息

Sensors (Basel). 2021 Aug 19;21(16):5591. doi: 10.3390/s21165591.

DOI:10.3390/s21165591
PMID:34451041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8402251/
Abstract

An indole-based fluorescent chemosensor was synthesized to detect Zn. displayed a marked fluorescence increment with Zn. The detection limit (0.41 μM) of for Zn was greatly below that suggested by the World Health Organization. can quantify Zn in real water samples. More significantly, could determine and depict the presence of Zn in zebrafish. The detecting mechanism of toward Zn was illustrated by fluorescence and UV-visible spectroscopy, DFT calculations, H NMR titration and ESI mass.

摘要

合成了一种基于吲哚的荧光化学传感器来检测 Zn。它对 Zn 显示出明显的荧光增强。该传感器对 Zn 的检测限(0.41 μM)大大低于世界卫生组织建议的水平。它可以定量测定实际水样中的 Zn。更重要的是,它可以在斑马鱼体内检测和描绘 Zn 的存在。通过荧光和紫外-可见光谱、DFT 计算、1H NMR 滴定和 ESI 质谱研究了 对 Zn 的检测机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/8402251/d263a5101e8d/sensors-21-05591-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/8402251/5c3f44342e3a/sensors-21-05591-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/8402251/657df7b62b12/sensors-21-05591-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/8402251/44b5e85ec88c/sensors-21-05591-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/8402251/0b38d1761178/sensors-21-05591-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/8402251/6e3938145eff/sensors-21-05591-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/8402251/d263a5101e8d/sensors-21-05591-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/8402251/5c3f44342e3a/sensors-21-05591-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/8402251/657df7b62b12/sensors-21-05591-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/8402251/44b5e85ec88c/sensors-21-05591-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/8402251/0b38d1761178/sensors-21-05591-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/8402251/6e3938145eff/sensors-21-05591-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5515/8402251/d263a5101e8d/sensors-21-05591-g004.jpg

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