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[脾切除术对白细胞吞噬功能的影响]

[Effect of splenectomy on phagocytic function of leucocytes].

作者信息

He S W

出版信息

Zhonghua Wai Ke Za Zhi. 1989 Jun;27(6):354-6, 381.

PMID:2582936
Abstract

By means of whole blood chemiluminescence, phagocytic function of leucocytes (PFL) and the opsonic activity of plasma (OAP) were examined in 27 patients to observe the effect of splenectomy on phagocytic function of leucocytes. It was found that, the PFL of splenectomized patients was significantly lower than that of healthy persons and patients with cholecystectomy. It was then believed that the impaired immunological function against infection in splenectomized patients was related to the abnormal PFL resulting from the disappearance of tuftsin in the circulation, an important leucocytic activator produced only in the spleen. It was showed in this paper that the whole blood chemiluminescence is a simple, rapid and useful method in detecting PFL and OAP.

摘要

通过全血化学发光法,对27例患者的白细胞吞噬功能(PFL)和血浆调理活性(OAP)进行检测,以观察脾切除对白细胞吞噬功能的影响。结果发现,脾切除患者的PFL显著低于健康人和胆囊切除患者。当时认为,脾切除患者抗感染免疫功能受损与循环中促吞噬素(仅在脾脏产生的一种重要白细胞激活剂)消失导致的PFL异常有关。本文表明,全血化学发光法是检测PFL和OAP的一种简便、快速且有用的方法。

相似文献

1
[Effect of splenectomy on phagocytic function of leucocytes].[脾切除术对白细胞吞噬功能的影响]
Zhonghua Wai Ke Za Zhi. 1989 Jun;27(6):354-6, 381.
2
[Chemiluminescence of whole blood--analysis of the kinetics and application of clinical examination of phagocytic functions of whole blood from various type of diseases].[全血化学发光——不同类型疾病全血吞噬功能临床检测的动力学分析及应用]
Hokkaido Igaku Zasshi. 1986 Nov;61(6):947-60.
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Nihon Kyobu Shikkan Gakkai Zasshi. 1989 Jan;27(1):57-63.
4
[Rapid chemiluminescence analysis of the effect of drugs on the functional activity of phagocytosing blood cells].
Farmakol Toksikol. 1989 Mar-Apr;52(2):97-100.
5
[Changes in the phagocytic activity of leukocytes in patients with acute appendicitis].[急性阑尾炎患者白细胞吞噬活性的变化]
Vestn Khir Im I I Grek. 1975 Feb;114(2):42-4.
6
The measurement of opsonic and phagocytic function by Luminol-dependent chemiluminescence.通过鲁米诺依赖的化学发光法测定调理吞噬功能。
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7
[Serum tuftsin concentration as an indicator of postoperative splenic function after spleen-preserving surgery].
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8
[Tuftsin].
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9
A new phagocytosis-stimulating tetrapeptide hormone, tuftsin, and its role in disease.
J Reticuloendothel Soc. 1972 Aug;12(2):197-215.
10
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