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急性生理与慢性健康状况评估II和格拉斯哥昏迷评分在预测麻醉后恢复室患者预后中的比较。

Comparison of acute physiology and chronic health evaluation II and Glasgow Coma Score in predicting the outcomes of Post Anesthesia Care Unit's patients.

作者信息

Hosseini Mohammad, Ramazani Jamileh

机构信息

Department of Nursing, North Khorasan University of Medical Sciences, Bojnourd, Iran.

Department of Nursing, Islamic Azad University, Bojnourd Branch, Bojnourd, Iran.

出版信息

Saudi J Anaesth. 2015 Apr-Jun;9(2):136-41. doi: 10.4103/1658-354X.152839.

DOI:10.4103/1658-354X.152839
PMID:25829900
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4374217/
Abstract

CONTEXT

Acute physiology and chronic health evaluation II (APACHE II) is one of the most general classification systems of disease severity in Intensive Care Units and Glasgow Coma Score (GCS) is one of the most specific ones.

AIMS

The aim of the current study was to assess APACHE II and GCS ability in predicting the outcomes (survivors, non-survivors) in the Post Anesthesia Care Unit's (PACU).

SETTINGS AND DESIGN

This was an observational and prospective study of 150 consecutive patients admitted in the PACU during 6-month period.

MATERIALS AND METHODS

Demographic information recorded on a checklist, also information about severity of disease calculated based on APACHE II scoring system in the first admission 24 h and GCS scale.

STATISTICAL ANALYSIS USED

Logistic regression, Hosmer-Lemeshow test and receiver operator characteristic (ROC) curves were used in statistical analysis (95% confidence interval).

RESULTS

Data analysis showed a significant statistical difference between outcomes and both APACHE II and Glasgow Coma Score (GCS) (P < 0.0001). The ROC-curve analysis suggested that the predictive ability of GCS is slightly better than APACHE II in this study. For GCS the area under the ROC curve was 86.1% (standard error [SE]: 3.8%), and for APACHE II it was 85.7% (SE: 3.5%), also the Hosmer-Lemeshow statistic revealed better calibration for GCS (χ(2) = 5.177, P = 0.521), than APACHE II (χ(2) = 10.203, P = 0.251).

CONCLUSIONS

The survivors had significantly lower APACHE II and higher GCS compared with non-survivors, also GCS showed more predictive accuracy than APACHE II in prognosticating the outcomes in PACU.

摘要

背景

急性生理与慢性健康状况评价系统II(APACHE II)是重症监护病房中最常用的疾病严重程度分类系统之一,而格拉斯哥昏迷评分(GCS)是最具特异性的系统之一。

目的

本研究旨在评估APACHE II和GCS预测麻醉后恢复室(PACU)患者结局(存活者、非存活者)的能力。

设置与设计

这是一项对6个月期间连续收治入PACU的150例患者进行的观察性前瞻性研究。

材料与方法

在检查表上记录人口统计学信息,同时记录首次入院24小时时基于APACHE II评分系统计算的疾病严重程度信息以及GCS评分。

所用统计分析方法

采用逻辑回归、Hosmer-Lemeshow检验和受试者工作特征(ROC)曲线进行统计分析(95%置信区间)。

结果

数据分析显示结局与APACHE II和格拉斯哥昏迷评分(GCS)之间存在显著统计学差异(P < 0.0001)。ROC曲线分析表明,在本研究中GCS的预测能力略优于APACHE II。GCS的ROC曲线下面积为86.1%(标准误[SE]:3.8%),APACHE II为85.7%(SE:3.5%),此外Hosmer-Lemeshow统计量显示GCS的校准优于APACHE II(χ(2) = 5.177,P = 0.521),而APACHE II为(χ(2) = 10.203,P = 0.251)。

结论

与非存活者相比,存活者的APACHE II评分显著更低,GCS评分更高,并且在预测PACU患者结局方面,GCS比APACHE II显示出更高的预测准确性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4334/4374217/89d73fa210bf/SJA-9-136-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4334/4374217/89d73fa210bf/SJA-9-136-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4334/4374217/89d73fa210bf/SJA-9-136-g004.jpg

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