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真菌β-葡聚糖的结构特征、技术功能和生理方面:综述。

Structural Characterization, Technological Functionality, and Physiological Aspects of Fungal β-D-glucans: A Review.

机构信息

a Unité de Science des Aliments et Formulation, Agro-Bio Tech, Université de Liège, Gembloux , Gembloux , Belgium.

b Unité de Bioindustries, Gembloux Agro-Bio Tech, Université de Liège , Gembloux , Belgium.

出版信息

Crit Rev Food Sci Nutr. 2016 Jul 26;56(10):1746-52. doi: 10.1080/10408398.2013.854733.

DOI:10.1080/10408398.2013.854733
PMID:25830657
Abstract

β-D-glucans are a (1→3)-linked glucose polymer with (1→6)-linked side chains and a major component of fungal cell walls. They exhibit structural integrity to the fungal cell wall. In addition, β-glucans are widely used as food adjuvant in food and pharmaceutical industries because of their physico-chemical properties. Several studies have focused on different isolation processes of (1→3) (1→6)-β-glucan that could affect the physico-chemical and functional properties of β-glucan such as chemical composition, solubility, viscosity, hydration properties, and oil binding capacity. Immunological activity is one of the most important properties of β-glucans. Thus, they are effective in inhibiting growth of cancer cells and metastasis and preventing bacterial infection. In humans, β-glucans reduce blood cholesterol, improve glucose absorption by body cells, and so help wound healing. This review described the prebiotic potentiality of fungal β-D-glucans with the objective to detail the methodologies applied for their extraction, their structure and techno-functional properties, and finally their biological effects.

摘要

β-葡聚糖是一种(1→3)连接的葡萄糖聚合物,带有(1→6)连接的侧链,是真菌细胞壁的主要成分。它们对真菌细胞壁具有结构完整性。此外,由于其物理化学性质,β-葡聚糖被广泛用作食品和制药工业中的食品添加剂。几项研究集中在(1→3)(1→6)-β-葡聚糖的不同分离工艺上,这些工艺可能会影响β-葡聚糖的物理化学和功能特性,如化学组成、溶解度、粘度、水合特性和油结合能力。免疫活性是β-葡聚糖最重要的特性之一。因此,它们能有效抑制癌细胞生长和转移,预防细菌感染。在人类中,β-葡聚糖可降低血液胆固醇,改善体细胞对葡萄糖的吸收,从而有助于伤口愈合。本综述描述了真菌β-D-葡聚糖的益生元潜力,目的是详细介绍用于提取它们的方法、它们的结构和技术功能特性,以及它们的生物学效应。

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