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β-葡聚糖对健康的促进作用:预防突变和癌症。

beta-Glucans in promoting health: prevention against mutation and cancer.

作者信息

Mantovani Mário S, Bellini Marilanda F, Angeli José Pedro F, Oliveira Rodrigo J, Silva Ariane F, Ribeiro Lúcia R

机构信息

Departamento de Biologia Geral, Universidade Estadual de Londrina, Londrina, PR, Brazil.

出版信息

Mutat Res. 2008 Mar-Apr;658(3):154-61. doi: 10.1016/j.mrrev.2007.07.002. Epub 2007 Aug 3.

Abstract

The polysaccharides beta-glucans occur as a principal component of the cellular walls. Some microorganisms, such as yeast and mushrooms, and also cereals such as oats and barley, are of economic interest because they contain large amounts of beta-glucans. These substances stimulate the immune system, modulating humoral and cellular immunity, and thereby have beneficial effect in fighting infections (bacterial, viral, fungal and parasitic). beta-Glucans also exhibit hypocholesterolemic and anticoagulant properties. Recently, they have been demonstrated to be anti-cytotoxic, antimutagenic and anti-tumorogenic, making them promising candidate as pharmacological promoters of health.

摘要

多糖β-葡聚糖是细胞壁的主要成分。一些微生物,如酵母和蘑菇,以及燕麦和大麦等谷物,因其含有大量β-葡聚糖而具有经济价值。这些物质刺激免疫系统,调节体液免疫和细胞免疫,从而在对抗感染(细菌、病毒、真菌和寄生虫)方面具有有益作用。β-葡聚糖还具有降胆固醇和抗凝血特性。最近,它们已被证明具有抗细胞毒性、抗诱变和抗肿瘤作用,使其成为有前景的健康药理学促进剂候选物。

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