Moonaz Steffany Haaz, Bingham Clifton O, Wissow Lawrence, Bartlett Susan J
From the Maryland University of Integrative Health, Laurel; Department of Medicine, and School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA; Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada.S.H. Moonaz, PhD, Maryland University of Integrative Health; C.O. Bingham III, MD, Department of Medicine, Division of Rheumatology, Johns Hopkins University; L. Wissow, MD, MPH, School of Public Health, Johns Hopkins University; S.J. Bartlett, PhD, Associate Professor of Medicine, Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University.
J Rheumatol. 2015 Jul;42(7):1194-202. doi: 10.3899/jrheum.141129. Epub 2015 Apr 1.
To evaluate the effect of Integral-based hatha yoga in sedentary people with arthritis.
There were 75 sedentary adults aged 18+ years with rheumatoid arthritis (RA) or knee osteoarthritis randomly assigned to 8 weeks of yoga (two 60-min classes and 1 home practice/wk) or waitlist. Poses were modified for individual needs. The primary endpoint was physical health [Medical Outcomes Study Short Form-36 (SF-36) physical component summary (PCS)] adjusted for baseline; exploratory adjusted outcomes included fitness, mood, stress, self-efficacy, SF-36 health-related quality of life (HRQOL), and RA disease activity. In everyone completing yoga, we explored longterm effects at 9 months.
Participants were mostly female (96%), white (55%), and college-educated (51%), with a mean (SD) age of 52 years (12 yrs). Average disease duration was 9 years and 49% had RA. At 8 weeks, yoga was associated with significantly higher PCS (6.5, 95% CI 2.0-10.7), walking capacity (125 m, 95% CI 15-235), positive affect (5.2, 95% CI 1.4-8.9), and lower Center for Epidemiologic Studies Depression Scale (-3.0, 95% CI -4.8 - -1.3). Significant improvements (p < 0.05) were evident in SF-36 role physical, pain, general health, vitality, and mental health scales. Balance, grip strength, and flexibility were similar between groups. Twenty-two out of 28 in the waitlist group completed yoga. Among all yoga participants, significant (p < 0.05) improvements were observed in mean PCS, flexibility, 6-min walk, and all psychological and most HRQOL domains at 8 weeks with most still evident 9 months later. Of 7 adverse events, none were associated with yoga.
Preliminary evidence suggests yoga may help sedentary individuals with arthritis safely increase physical activity, and improve physical and psychological health and HRQOL. Clinical Trials NCT00349869.
评估基于整体练习的哈他瑜伽对久坐不动的关节炎患者的影响。
75名年龄在18岁及以上、患有类风湿性关节炎（RA）或膝骨关节炎的久坐不动的成年人被随机分配，一组进行为期8周的瑜伽练习（每周两次60分钟课程和1次家庭练习），另一组进入候补名单。体式根据个人需求进行调整。主要终点是经基线调整后的身体健康状况[医学结果研究简明健康调查问卷（SF-36）身体成分总结（PCS）]；探索性调整后的结果包括健康状况、情绪、压力、自我效能感、SF-36健康相关生活质量（HRQOL）以及RA疾病活动度。对于所有完成瑜伽练习的人，我们在9个月时探索了长期效果。
参与者大多为女性（96%）、白人（55%）且受过大学教育（51%），平均（标准差）年龄为52岁（12岁）。平均病程为9年，49%的人患有RA。在8周时，瑜伽与显著更高的PCS（6.5，95%置信区间2.0 - 10.7）、步行能力（125米，95%置信区间15 - 235）、积极情绪（5.2，95%置信区间1.4 - 8.9）以及更低的流行病学研究中心抑郁量表得分（-3.0，95%置信区间 - 4.8 - -1.3）相关。SF-36角色功能、疼痛、总体健康、活力和心理健康量表有显著改善（p < 0.05）。两组之间的平衡能力、握力和柔韧性相似。候补名单组的28人中有22人完成了瑜伽练习。在所有瑜伽参与者中，8周时平均PCS、柔韧性、6分钟步行距离以及所有心理和大多数HRQOL领域均有显著（p < 0.05）改善，且在9个月后大多数改善仍然明显。7起不良事件中，无一与瑜伽相关。
初步证据表明，瑜伽可能有助于久坐不动的关节炎患者安全地增加身体活动，并改善身体和心理健康以及HRQOL。临床试验编号：NCT00349869。
