Ritsner M S
Genetika. 1989 Aug;25(8):1473-9.
The results of the genetic-correlative analysis of schizophrenia (681 families) and epilepsy (365 families) are given. The presence of various liabilities to these diseases, having genetic correlation of 0.16-0.19 between them, is shown. From epidemiologic data, elevated frequency of convulsive manifestations in schizophrenics and schizophrenia-like psychosis in epileptic patients was established. Within the limits of the three-component hypothesis of etiology of these diseases ("major genes", environmental factors and constitutional readiness), the relation detected is explained by interaction between constitutional readiness factors.
给出了精神分裂症（681个家庭）和癫痫（365个家庭）的遗传相关性分析结果。结果表明，这两种疾病存在各种易感性，它们之间的遗传相关性为0.16 - 0.19。从流行病学数据可知，精神分裂症患者抽搐表现的频率升高，癫痫患者中类似精神分裂症的精神病发病率也升高。在这两种疾病病因的三因素假说（“主基因”、环境因素和体质易感性）范围内，所检测到的关系是由体质易感性因素之间的相互作用来解释的。
