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身体疾病作为老年人自杀的预测因素:一项基于全国登记数据的队列研究。

Physical diseases as predictors of suicide in older adults: a nationwide, register-based cohort study.

作者信息

Erlangsen Annette, Stenager Elsebeth, Conwell Yeates

机构信息

The Research Unit, Mental Health Centre Copenhagen and Faculty of Health Sciences, Bispebjerg Bakke 23, 2400, Copenhagen NV, Denmark.

Department of Mental Health, Johns Hopkins School of Public Health, Baltimore, MD, USA.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2015 Sep;50(9):1427-39. doi: 10.1007/s00127-015-1051-0. Epub 2015 Apr 3.

Abstract

PURPOSE

The objective of the study was to examine the association between 39 physical diseases and death by suicide in older adults.

METHODS

Individual-level register data on all older adults aged 65 years and over living in Denmark during 1990-2009 (N = 1,849,110) were analysed. Rate ratios were calculated for 39 physical diseases while adjusting for period, age group, conjugal status, income, physical comorbidity, and psychiatric disorders.

RESULTS

In all, 4792 older adults aged 65+ died by suicide during the follow-up of >16 million person-years. Gastrointestinal cancer was linked to a rate ratio of 2.5 (95 % CI 1.9-3.5) in men while excess suicide risk for women with brain cancer was 3.5 (95 % CI 1.1-10.8) within three years of diagnosis. Men and women diagnosed with liver diseases within three years experienced a 2.7- (95 % CI 1.7-4.2) and 4.0- (95 % CI 2.5-6.4) fold higher risk of suicide, respectively, than those not diagnosed. Elevated risks of suicide were identified for lung cancer, gastrointestinal cancer, breast cancer, genital cancer, bladder cancer, lymph node cancer, epilepsy, cerebrovascular diseases, cataract, heart diseases, chronic obstructive pulmonary disorders (COPD), gastrointestinal disease, liver disease, arthritis, osteoporosis, prostate disorders, male genital disorders, and spinal fracture when compared to persons not diagnosed within three years.

CONCLUSIONS

Multiple physical diseases were linked to increased risks of suicide in older adults. Increased attention to suicidal ideation and risk assessment might be warranted during the diagnosis and treatment of these disorders.

摘要

目的

本研究的目的是调查39种身体疾病与老年人自杀死亡之间的关联。

方法

分析了1990年至2009年期间居住在丹麦的所有65岁及以上老年人的个体层面登记数据(N = 1,849,110)。计算了39种身体疾病的发病率比,同时对时期、年龄组、婚姻状况、收入、身体合并症和精神疾病进行了调整。

结果

在超过1600万人年的随访期间,共有4792名65岁及以上的老年人自杀死亡。男性胃肠道癌的发病率比为2.5(95%CI 1.9 - 3.5),而女性脑癌患者在诊断后三年内自杀风险增加3.5(95%CI 1.1 - 10.8)。在三年内被诊断患有肝病的男性和女性自杀风险分别比未被诊断者高2.7倍(95%CI 1.7 - 4.2)和4.0倍(95%CI 2.5 - 6.4)。与三年内未被诊断的人相比,肺癌、胃肠道癌、乳腺癌、生殖器癌、膀胱癌、淋巴结癌、癫痫、脑血管疾病、白内障、心脏病、慢性阻塞性肺疾病(COPD)、胃肠道疾病、肝病、关节炎、骨质疏松症、前列腺疾病、男性生殖器疾病和脊柱骨折患者的自杀风险升高。

结论

多种身体疾病与老年人自杀风险增加有关。在这些疾病的诊断和治疗过程中,可能有必要更加关注自杀意念和风险评估。

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