Altmann Aline Segatto Pires, Collares Fabrício Mezzomo, Ogliari Fabrício Aulo, Samuel Susana Maria Werner
Graduate student, Dental Materials Laboratory, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Adjunct professor, Dental Materials Laboratory, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Am J Orthod Dentofacial Orthop. 2015 Apr;147(4 Suppl):S82-7. doi: 10.1016/j.ajodo.2015.01.015.
Antibacterial adhesives were developed to reduce the incidence of white spot lesions in orthodontic patients. Compounds that contain triazine are known as effective antibacterial agents. The aims of this study were to develop an experimental orthodontic adhesive containing 1,3,5-triacryloylhexahydro-1,3,5-triazine (TAT) and to characterize it.
TAT was added in 3 concentrations (10%, 15%, and 20%) to the experimental orthodontic adhesive. Antibacterial activity was assayed by brain-heart infusion broth dilution against Streptococcus mutans. The degree of conversion was measured using Fourier transform infrared spectroscopy, and solvent degradation was evaluated by Knoop microhardness before and after immersion in ethanol for 2 hours. The shear bond strength of metal brackets bonded to bovine enamel surface was assessed.
All experimental adhesives reduced bacterial growth. The addition of 15% and 20% TAT increased the degree of conversion compared with the control group (0%) and the 10% group. All groups showed a decrease in hardness after ethanol immersion, and there was also a decrease in the percentage of variation of Knoop hardness in the experimental adhesives containing TAT, whereas the shear bond strength increased.
Orthodontic adhesives containing TAT are promising antibacterial materials, especially those with 15% and 20% TAT.
抗菌正畸粘合剂旨在降低正畸患者白斑病变的发生率。含三嗪的化合物是已知的有效抗菌剂。本研究的目的是开发一种含1,3,5 - 三丙烯酰基六氢 - 1,3,5 - 三嗪（TAT）的实验性正畸粘合剂并对其进行表征。
将TAT以3种浓度（10%、15%和20%）添加到实验性正畸粘合剂中。采用脑心浸液肉汤稀释法测定对变形链球菌的抗菌活性。使用傅里叶变换红外光谱法测量转化率，并通过努氏显微硬度评估在乙醇中浸泡2小时前后的溶剂降解情况。评估金属托槽与牛牙釉质表面粘结的剪切粘结强度。
所有实验性粘合剂均降低了细菌生长。与对照组（0%）和10%组相比，添加15%和20% TAT提高了转化率。所有组在乙醇浸泡后硬度均降低，含TAT的实验性粘合剂中努氏硬度变化百分比也降低，而剪切粘结强度增加。
含TAT的正畸粘合剂是有前景的抗菌材料，尤其是含15%和20% TAT的粘合剂。
