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利用Illumina和PacBio技术对II型聚酮类抗生素阿齐霉素的产生菌放线菌Kibdelosporangium sp. MJ126-NF4进行高质量基因组草图测序

High-Quality Draft Genome Sequence of Actinobacterium Kibdelosporangium sp. MJ126-NF4, Producer of Type II Polyketide Azicemicins, Using Illumina and PacBio Technologies.

作者信息

Ogasawara Yasushi, Torrez-Martinez Norah, Aragon Anthony D, Yackley Benjamin J, Weber Jessica A, Sundararajan Anitha, Ramaraj Thiruvarangan, Edwards Jeremy S, Melançon Charles E

机构信息

Department of Chemistry and Chemical Biology, University of New Mexico, Albuquerque, New Mexico, USA.

Department of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.

出版信息

Genome Announc. 2015 Apr 2;3(2):e00114-15. doi: 10.1128/genomeA.00114-15.

DOI:10.1128/genomeA.00114-15
PMID:25838474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4384478/
Abstract

Here, we report the high-quality draft genome sequence of actinobacterium Kibdelosporangium sp. MJ126-NF4, producer of the type II polyketide azicemicins, obtained using Illumina and PacBio sequencing technologies. The 11.75-Mbp genome contains >11,000 genes and 22 polyketide and nonribosomal peptide natural product gene clusters.

摘要

在此，我们报告了放线菌Kibdelosporangium sp. MJ126-NF4的高质量基因组草图序列，该菌株是II型聚酮化合物氮杂霉素的产生菌，使用Illumina和PacBio测序技术获得。该1175万碱基对的基因组包含超过11000个基因以及22个聚酮化合物和非核糖体肽天然产物基因簇。

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