Prasad Kavitha, Dexith Jayashree, Lalitha R M, Ranganath K, Shuba R, Kumari M Kalpana, Mysorekar Vijaya
Department of Oral and Maxillofacial Surgery, M.S.Ramaiah Dental College and Hospital, New BEL Road, M.S.Ramaiah Nagar, MSRIT post, Bangalore, 560 054 Karnataka India.
Department of Pathology, M.S.Ramaiah Medical College, Bangalore, India.
J Maxillofac Oral Surg. 2015 Mar;14(Suppl 1):87-92. doi: 10.1007/s12663-012-0338-x. Epub 2012 Feb 25.
Osteosarcomas are highly malignant bone tumours. Its appearance in craniofacial bones is a rare entity and accounts for only 1% of all head and neck malignancies. We present an uncommon case report of a 42 year old male patient with osteosarcoma of left maxilla, which was successfully excised under general anesthesia. The patient reported to us with a history of pain, swelling, pus discharge and tooth extraction, which led to the differential diagnosis of suppurative osteomyelitis, dentoalveolar abscess, benign odontogenic tumour, an infected cyst etc. Histopathological examination of incisional biopsy was reported as chondromyxoid fibroma which is a rare benign tumour. However the excisional biopsy specimen was reported as osteosarcoma of maxilla. The clinical presentation, diagnostic challenges and its therapeutic approach are addressed. This case serves to emphasize the need to recognize osteosarcoma when it presents in unexpected locations, especially because of its rarity.
骨肉瘤是高度恶性的骨肿瘤。它出现在颅面骨中是一种罕见的情况,仅占所有头颈部恶性肿瘤的1%。我们报告一例罕见病例,一名42岁男性患者患有左上颌骨骨肉瘤,在全身麻醉下成功切除。该患者前来就诊时伴有疼痛、肿胀、流脓和拔牙史,这导致了化脓性骨髓炎、牙槽脓肿、良性牙源性肿瘤、感染性囊肿等的鉴别诊断。切开活检的组织病理学检查报告为软骨黏液样纤维瘤,这是一种罕见的良性肿瘤。然而,切除活检标本报告为上颌骨骨肉瘤。本文讨论了其临床表现、诊断挑战及其治疗方法。该病例强调了在骨肉瘤出现在意想不到的部位时识别它的必要性,特别是因为其罕见性。