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本文引用的文献

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Template based rotation: a method for functional connectivity analysis with a priori templates.基于模板的旋转:一种使用先验模板进行功能连接性分析的方法。
Neuroimage. 2014 Nov 15;102 Pt 2(0 2):620-36. doi: 10.1016/j.neuroimage.2014.08.022. Epub 2014 Aug 21.
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Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease.淀粉样蛋白和 APOE ε4 相互作用影响临床前阿尔茨海默病的短期衰退。
Neurology. 2014 May 20;82(20):1760-7. doi: 10.1212/WNL.0000000000000431. Epub 2014 Apr 18.
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The encoding/retrieval flip: interactions between memory performance and memory stage and relationship to intrinsic cortical networks.编码/检索翻转:记忆表现和记忆阶段之间的相互作用,以及与内在皮质网络的关系。
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Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.为了定义阿尔茨海默病的临床前阶段:来自美国国家老龄化研究所-阿尔茨海默病协会工作组关于阿尔茨海默病诊断指南的建议。
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Resistance to forgetting associated with hippocampus-mediated reactivation during new learning.新学习过程中海马介导的再激活与遗忘抵抗有关。
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Generalizability of two methods of estimating premorbid intelligence in the elderly.两种估算老年人病前智力方法的可推广性。
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哈佛衰老大脑研究:数据集与可获取性。

Harvard Aging Brain Study: Dataset and accessibility.

作者信息

Dagley Alexander, LaPoint Molly, Huijbers Willem, Hedden Trey, McLaren Donald G, Chatwal Jasmeer P, Papp Kathryn V, Amariglio Rebecca E, Blacker Deborah, Rentz Dorene M, Johnson Keith A, Sperling Reisa A, Schultz Aaron P

机构信息

Harvard Aging Brain Study, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA.

Harvard Aging Brain Study, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA.

出版信息

Neuroimage. 2017 Jan;144(Pt B):255-258. doi: 10.1016/j.neuroimage.2015.03.069. Epub 2015 Apr 3.

DOI:10.1016/j.neuroimage.2015.03.069
PMID:25843019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4592689/
Abstract

The Harvard Aging Brain Study is sharing its data with the global research community. The longitudinal dataset consists of a 284-subject cohort with the following modalities acquired: demographics, clinical assessment, comprehensive neuropsychological testing, clinical biomarkers, and neuroimaging. To promote more extensive analyses, imaging data was designed to be compatible with other publicly available datasets. A cloud-based system enables access to interested researchers with blinded data available contingent upon completion of a data usage agreement and administrative approval. Data collection is ongoing and currently in its fifth year.

摘要

哈佛衰老大脑研究正在向全球研究界分享其数据。该纵向数据集由一个284名受试者的队列组成,采集了以下数据模式:人口统计学、临床评估、全面的神经心理学测试、临床生物标志物和神经影像学。为了促进更广泛的分析,成像数据被设计为与其他公开可用的数据集兼容。一个基于云的系统使感兴趣的研究人员能够访问数据,这些数据在完成数据使用协议并获得行政批准后以盲态形式提供。数据收集工作正在进行中,目前处于第五年。