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洛替拉康B和巴拉菲康A硅水凝胶绷带式隐形眼镜在减轻准分子激光原位角膜磨镶术后疼痛和不适方面的比较:一项对侧眼研究。

Comparison of Lotrafilcon B and Balafilcon A silicone hydrogel bandage contact lenses in reducing pain and discomfort after photorefractive keratectomy: A contralateral eye study.

作者信息

Mohammadpour Mehrdad, Amouzegar Afsaneh, Hashemi Hassan, Jabbarvand Mahmoud, Kordbacheh Hamed, Rahimi Firoozeh, Hashemian Mohammad Naser

机构信息

Ophthalmology Department and Eye Research Center, Farabi Eye Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Ophthalmology Department and Eye Research Center, Farabi Eye Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Cont Lens Anterior Eye. 2015 Jun;38(3):211-4. doi: 10.1016/j.clae.2015.01.014. Epub 2015 Apr 2.

Abstract

PURPOSE

To assess the effect of two silicone hydrogel contact lenses with high oxygen permeability in patients having photorefractive keratectomy (PRK).

SETTING

Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

METHODS

Sixty patients (120 eyes) who had bilateral PRK were enrolled in this double blind clinical trial. Each patient was fitted with a Lotrafilcon B (Air Optix(®)AQUA, Ciba Vision, Duluth, GA, USA) lens in one eye and a Balafilcon A (PureVision™ Bausch & Lomb, Rochester, NY, USA) lens in the fellow eye. Patients' responses to a subjective questionnaire in terms of pain, foreign body sensation, photophobia, blurred vision and epiphora were evaluated on the first and third postoperative days.

RESULTS

Mean pain score for Lotrafilcon B and Balafilcon A contact lenses was 4.43±3.18 vs. 5.45±3.37 on the first postoperative day and 3.43±3.23 vs. 3.88±3.01 on the third postoperative day. However, the difference was only significant in the first 24h after surgery (P=0.032). Foreign body sensation was clinically higher with Balafilcon A contact lens (5.0±3.47 vs. 4.08±3.34 on day 1 and 4.98±3.52 vs. 3.55±3.20 on day 3) and the difference was statistically significant on the first and the third postoperative days (P=0.042 and 0.002, respectively). There was no statistically significant difference between two contact lenses in terms of photophobia, epiphora and blurred vision (P>0.05).

CONCLUSION

The Lotrafilcon B lens resulted in significantly less postoperative pain and discomfort after PRK, especially in the first 24h after PRK.

摘要

目的

评估两种高透氧性硅水凝胶隐形眼镜对接受准分子激光角膜切削术(PRK)患者的影响。

地点

伊朗德黑兰医科大学法拉比眼科医院。

方法

60例接受双侧PRK的患者(120只眼)纳入这项双盲临床试验。每位患者一只眼佩戴Lotrafilcon B(美国佐治亚州德卢斯市汽巴视觉公司的爱尔康水润型)镜片,另一只眼佩戴Balafilcon A(美国纽约州罗切斯特市博士伦公司的纯视)镜片。在术后第1天和第3天评估患者对关于疼痛、异物感、畏光、视物模糊和溢泪的主观问卷的反应。

结果

Lotrafilcon B和Balafilcon A隐形眼镜的平均疼痛评分在术后第1天分别为4.43±3.18和5.45±3.37;在术后第3天分别为3.43±3.23和3.88±3.01。然而,差异仅在术后最初24小时具有统计学意义(P =0.032)。Balafilcon A隐形眼镜的异物感在临床上更高(第1天为5.0±3.47比4.08±3.34,第3天为4.98±3.52比3.55±3.20),且差异在术后第1天和第3天具有统计学意义(分别为P =0.042和0.002)。两种隐形眼镜在畏光、溢泪和视物模糊方面无统计学显著差异(P>0.05)。

结论

Lotrafilcon B镜片在PRK术后导致的疼痛和不适显著更少,尤其是在PRK术后的最初24小时。

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