Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
Cont Lens Anterior Eye. 2020 Jun;43(3):244-249. doi: 10.1016/j.clae.2020.02.005. Epub 2020 Feb 23.
To compare the efficiency and safety of two bandage contact lenses after photorefractive keratectomy (PRK).
In this double-blind study, 45 patients (90 eyes) received PRK in both eyes and wore bandage contact lenses (BCLs), PureVision (Bausch & Lomb, Rochester, NY, USA) in one eye and PureVision2 (Bausch & Lomb, Rochester, NY, USA) in the other eye, randomly assigned. The medication regimen after surgery was the same for both eyes. The epithelial defect's size, conjunctival hyperemia and lens centration were graded objectively using slit-lamp biomicroscopy on days 1, 3 and 5 after surgery. Also ocular symptoms of discomfort including tearing, photophobia, foreign body sensation and visual fluctuations were assessed subjectively at each visit.
The mean epithelial defect size on the first day after operation was similar in eyes fitted with PureVision (30.08 ± 5.30 mm²) and PureVision2 (30.25 ± 5.72 mm) lenses. (p = 0.79) Contact lens deposits and bulbar hyperaemia on days 1 and 3 after PRK were similar between the two eyes, but were significantly greater on day 5 for PureVision2 lenses. (p = 0.02; p = 0.04 respectively) There was no difference in contact lens decentration, and discomfort symptoms including pain, tearing, foreign body sensation, photophobia and visual fluctuations between the eyes fitted with PureVision and PureVision2. (p > 0.05) CONCLUSIONS: PureVision and PureVision2 contact lenses are equivalent as bandage lenses in important aspects such as corneal re-epithelialization and subjective comfort., although PureVision2 led to a higher incidence of contact lens deposits and conjunctival hyperemia early post-PRK.
比较两种绷带接触镜在准分子激光角膜切削术后的效果和安全性。
在这项双盲研究中，45 名患者（90 只眼）双眼均接受准分子激光角膜切削术，并随机分配佩戴绷带接触镜（BCL），其中一只眼佩戴PureVision（美国纽约州罗彻斯特的 Bausch & Lomb），另一只眼佩戴 PureVision2（美国纽约州罗彻斯特的 Bausch & Lomb）。术后两种眼的用药方案相同。术后第 1、3 和 5 天，使用裂隙灯生物显微镜客观评估上皮缺损大小、结膜充血和镜片定位情况。每次就诊时还评估眼部不适症状，包括流泪、畏光、异物感和视觉波动。
术后第 1 天，佩戴 PureVision（30.08±5.30mm²）和 PureVision2（30.25±5.72mm²）镜片的眼睛，平均上皮缺损大小相似。（p=0.79）PRK 后第 1 和第 3 天，两种镜片的接触镜沉积物和球结膜充血相似，但第 5 天 PureVision2 镜片的情况明显更严重。（p=0.02；p=0.04）两种镜片的镜片偏位无差异，佩戴 PureVision 和 PureVision2 镜片的眼睛的不适症状，包括疼痛、流泪、异物感、畏光和视觉波动，均无差异。（p>0.05）
在角膜再上皮化和主观舒适度等重要方面，PureVision 和 PureVision2 接触镜作为绷带镜是等效的，尽管 PureVision2 在 PRK 后早期导致更高的接触镜沉积物和结膜充血发生率。
