Mohammadpour Mehrdad, Heidari Zahra, Hashemi Hassan, Asgari Soheila
Ophthalmology Department (M.M. and Z.H.), Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran; Noor Ophthalmology Research Center (M.M., Z.H., and S.A.), Noor Eye Hospital, Tehran, Iran; and Noor Research Center for Ophthalmic Epidemiology (H.H.), Noor Eye Hospital, Tehran, Iran.
Eye Contact Lens. 2018 Nov;44 Suppl 2:S273-S276. doi: 10.1097/ICL.0000000000000471.
To compare the lotrafilcon B and comfilcon A silicone hydrogel bandage contact lenses after photorefractive keratectomy (PRK).
One hundred twenty eyes of 60 patients who underwent PRK were included in this randomized clinical trial study. In the end of the surgery, the lotrafilcon B (Air Optix; Ciba Vision, Duluth, GA) was used in one eye and the comfilcon A (Biofinity; Coopervision, Fairport, NY) was used in the fellow eye randomly. Pain and discomfort were assessed on the first and third day after surgery by visual analogue scale.
The mean pain score was 3.75±3.32 and 4.47±3.60 on the first day (P=0.253) and 3.63±3.48 and 4.16±3.60 on the third day (P=0.416) after the use of the lotrafilcon B and comfilcon A, respectively. The results showed no significant difference between the two groups (P=0.823). The mean score of foreign body sensation was 4.31±3.38 and 5.49±3.04 on the first day (P=0.045) and 4.44±3.34 and 5.13±3.23 on the third day (P=0.250) after the use of the lotrafilcon B and comfilcon A, respectively. The comfilcon A lens caused a more severe foreign body sensation only on the first day. There was no significant difference in photophobia, epiphora, and blurred vision between the two lenses (P>0.05).
Both lotrafilcon B and comfilcon A silicone hydrogel bandage contact lenses reduce clinical symptoms after PRK effectively. We found no difference in pain control and discomfort between them. However, the patients using the lotrafilcon B lens showed less foreign body sensation on the first day postoperatively.
比较准分子激光原位角膜磨镶术（PRK）后 lotrafilcon B 和 comfilcon A 硅水凝胶绷带式隐形眼镜的效果。
本随机临床试验研究纳入了 60 例行 PRK 的患者的 120 只眼。手术结束时，一只眼随机使用 lotrafilcon B（Air Optix；Ciba Vision，佐治亚州德卢斯），另一只眼随机使用 comfilcon A（Biofinity；Coopervision，纽约州费尔波特）。术后第一天和第三天通过视觉模拟量表评估疼痛和不适情况。
使用 lotrafilcon B 和 comfilcon A 后，第一天的平均疼痛评分分别为 3.75±3.32 和 4.47±3.60（P = 0.253），第三天分别为 3.63±3.48 和 4.16±3.60（P = 0.416）。结果显示两组之间无显著差异（P = 0.823）。使用 lotrafilcon B 和 comfilcon A 后，第一天的平均异物感评分为 4.31±3.38 和 5.49±3.04（P = 0.045），第三天分别为 4.44±3.34 和 5.13±3.23（P = 0.250）。仅在第一天，comfilcon A 镜片引起的异物感更严重。两种镜片在畏光、流泪和视力模糊方面无显著差异（P>0.05）。
lotrafilcon B 和 comfilcon A 硅水凝胶绷带式隐形眼镜均可有效减轻 PRK 后的临床症状。我们发现它们在疼痛控制和不适方面没有差异。然而，使用 lotrafilcon B 镜片的患者在术后第一天的异物感较轻。
