Kim Kyu Young, Jeon Seong Woo, Yang Hea Min, Lee Yu Rim, Kang Eun Jeong, Lee Hyun Seok, Kim Sung Kook
Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
Clin Endosc. 2015 Mar;48(2):147-51. doi: 10.5946/ce.2015.48.2.147. Epub 2015 Mar 27.
BACKGROUND/AIMS: Argon plasma coagulation (APC) has some merits in the treatment of gastric neoplasms including a shorter operative time and fewer complications compared with endoscopic mucosal resection or endoscopic submucosal dissection. However, there are few reports on the outcomes of gastric neoplasms treated using APC. The aim of this study was to evaluate APC in the treatment of early gastric neoplasms in terms of clinical efficacy, safety, and local recurrence.
We enrolled 28 patients who received APC therapy at the Kyungpook National University Hospital between May 2007 and April 2013. Clinical outcomes were analyzed.
The median follow-up period was 24.8 months (range, 2 to 78). Among the 28 lesions treated using the APC procedure, tumor recurrence was encountered in seven lesions (25.0%). Recurrence was found in 50% (5/10) of single APC cases and 11% (2/18) of rescue APC cases. The mean time to recurrence was 16.1 months (range, 2 to 78). There were no serious APC-related complications such as perforation, bleeding, or infection.
APC therapy can be a useful treatment with a favorable safety profile for patients with early gastric neoplasms. However, further studies are necessary to determine the long-term prognosis of patients undergoing this treatment.
背景/目的：与内镜黏膜切除术或内镜黏膜下剥离术相比，氩离子凝固术（APC）在治疗胃肿瘤方面具有一些优点，包括手术时间短和并发症少。然而，关于使用APC治疗胃肿瘤的结果的报道很少。本研究的目的是从临床疗效、安全性和局部复发方面评估APC在早期胃肿瘤治疗中的应用。
我们纳入了2007年5月至2013年4月在庆北国立大学医院接受APC治疗的28例患者。分析临床结果。
中位随访期为24.8个月（范围2至78个月）。在使用APC程序治疗的28个病变中，7个病变（25.0%）出现肿瘤复发。单发APC病例的复发率为50%（5/10），补救性APC病例的复发率为11%（2/18）。复发的平均时间为16.1个月（范围2至78个月）。没有发生与APC相关的严重并发症，如穿孔、出血或感染。
APC治疗对于早期胃肿瘤患者可能是一种安全有效的治疗方法。然而，需要进一步研究以确定接受该治疗患者的长期预后。
