女性皮肤黑色素瘤
Cutaneous Melanoma in Women.
作者信息
Roh Mi Ryung, Eliades Philip, Gupta Sameer, Tsao Hensin
机构信息
Wellman Center for Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, U.S.A ; Department of Dermatology, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Wellman Center for Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, U.S.A ; Tufts University School of Medicine, Boston, MA.
出版信息
Int J Womens Dermatol. 2015 Feb 1;1(1):21-25. doi: 10.1016/j.ijwd.2015.01.001.
The incidence of cutaneous melanoma (CM) continues to increase in the Caucasian population in the United States. In 2014, women only accounted for 42% of the 76,100 new melanoma cases and only 33% of the 9,710 deaths associated with CM in the US. These trends are consistently observed in populations around the world. Indeed, gender disparity in melanoma outcome is so consistently observed that gender has been suggested as an important prognostic factor in melanoma, despite not being formerly incorporated in staging algorithms. The source of this gender disparity in melanoma remains unclear but likely represents both biological and behavioral etiologies. Herein, we review the current knowledge of how melanoma differs between men and women.
在美国白种人群中，皮肤黑色素瘤（CM）的发病率持续上升。2014年，在美国76100例新发黑色素瘤病例中，女性仅占42%；在与CM相关的9710例死亡病例中，女性仅占33%。世界各地的人群中均持续观察到这些趋势。事实上，黑色素瘤预后的性别差异一直很明显，以至于尽管性别以前未被纳入分期算法，但有人提出性别是黑色素瘤的一个重要预后因素。黑色素瘤中这种性别差异的根源尚不清楚，但可能涉及生物学和行为学病因。在此，我们综述了目前关于男性和女性黑色素瘤差异的知识。
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