Wang Kuilong, Yu Hongli, Wu Hao, Wang Xinzhi, Pan Yaozong, Chen Yeqing, Liu Liping, Jin Yangping, Zhang Chenchao
a School of Pharmacy, Nanjing University of Chinese Medicine , Nanjing 210023 , P.R. China.
Nat Prod Res. 2015;29(15):1456-60. doi: 10.1080/14786419.2015.1027704. Epub 2015 Apr 7.
A new casbane diterpenoid, referred to as pekinenin G, together with one cembrane diterpene and four known casbane diterpenoids were isolated from the roots of Euphorbia pekinensis. Their structures were elucidated on the basis of spectroscopic studies and comparison with related known compounds. The six compounds showed different cytotoxic activities against four human cancer cell lines.
从大戟的根中分离出一种新的卡斯巴烷二萜,称为北京大戟素G,以及一种西松烷二萜和四种已知的卡斯巴烷二萜。通过光谱研究并与相关已知化合物进行比较,阐明了它们的结构。这六种化合物对四种人类癌细胞系表现出不同的细胞毒性活性。