Chipiti Talent, Ibrahim Mohammed Auwal, KOoorbanally Neil Anthony, Islam Md Shahidul
Acta Pol Pharm. 2015 Jan-Feb;72(1):119-27.
The study was intended to explore the antioxidant potential and phytochemical content of the ethanol and aqueous extracts of the leaf and root samples of Cissus cornifolia (Baker) Splanch (Vitaceae) across a series of four in vitro models. The results showed that all the extracts had reducing power (Fe(3+) - Fe2+) and DPPH, hydroxyl and nitric oxide radical scavenging abilities to varying extents. However, the ethanol root extract had more potent antioxidant power in all the experimental models than other extracts and possessed a higher total phenol content of 136.1 ± 6.7 mg/g. The GC-MS analysis of the aqueous and ethanol extracts of the roots indicated the presence of the common aromatic phenolic compounds, pyrogallol, resorcinol and catechol, a fatty acid, n-hexadecanoic acid and an aldehyde, vanillin. Data from this study suggest that both the leaves and roots of C. cornifolia possessed anti-oxidative activities with the best anti-oxidant activity being exhibited by the ethanolic extract of the root. The antioxidant properties of the root extracts can be attributed to the phenolic compounds present in the extracts.
本研究旨在通过一系列四种体外模型，探究乌蔹莓（Cissus cornifolia (Baker) Splanch，葡萄科）叶和根样本的乙醇提取物和水提取物的抗氧化潜力及植物化学成分。结果表明，所有提取物均具有不同程度的还原能力（Fe(3+) - Fe2+）以及清除DPPH、羟基和一氧化氮自由基的能力。然而，在所有实验模型中，乙醇根提取物比其他提取物具有更强的抗氧化能力，并拥有更高的总酚含量，为136.1 ± 6.7 mg/g。根的水提取物和乙醇提取物的气相色谱-质谱分析表明，存在常见的芳香酚类化合物连苯三酚、间苯二酚和儿茶酚、一种脂肪酸正十六烷酸以及一种醛香草醛。本研究数据表明，乌蔹莓的叶和根均具有抗氧化活性，其中根的乙醇提取物表现出最佳抗氧化活性。根提取物的抗氧化特性可归因于提取物中存在的酚类化合物。
