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用甲苯咪唑治疗细粒棘球绦虫包虫病。

Treatment of Echinococcus granulosus hydatid disease with mebendazole.

作者信息

Teggi A, Capozzi A, De Rosa F

机构信息

1st University of Rome, 2nd Chair of Infectious Diseases, Italy.

出版信息

J Chemother. 1989 Oct;1(5):310-7. doi: 10.1080/1120009x.1989.11738914.

DOI:10.1080/1120009x.1989.11738914
PMID:2585032
Abstract

The Authors report their personal experience in the treatment of 70 patients with hydatid cysts of different localization with mebendazole, following protocols approved by WHO. During treatment patients were submitted to careful clinical, biochemical, radiological and immunological controls. On the whole, 150 hydatid cysts and 13 cases of widespread hydatidosis were observed. Follow-up ranged from 6 months to 5 years. Morphological and/or volumetric modifications were observed in 64.3% of the total number of cysts treated, regardless of their localization. 9 relapses were observed, and all but one case showed the same previous sensitivity to a further cycle of mebendazole. The observed side effects were not severe.

摘要

作者报告了他们按照世界卫生组织批准的方案,使用甲苯达唑治疗70例不同部位包虫囊肿患者的个人经验。治疗期间,对患者进行了仔细的临床、生化、放射学和免疫学检查。总体而言,观察到150个包虫囊肿和13例播散性包虫病病例。随访时间为6个月至5年。无论囊肿位于何处,在接受治疗的囊肿总数中,64.3%观察到形态和/或体积改变。观察到9例复发,除1例病例外,所有病例对甲苯达唑的进一步疗程均表现出与之前相同的敏感性。观察到的副作用并不严重。

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