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低流行地区静脉注射吸毒者中艾滋病病毒感染情况介绍。

Introduction of HIV infection among intravenous drug abusers in low prevalence areas.

作者信息

Battjes R J, Pickens R W, Amsel Z

机构信息

National Institute on Drug Abuse, Rockville, MD 20857.

出版信息

J Acquir Immune Defic Syndr (1988). 1989;2(6):533-9.

PMID:2585246
Abstract

To explore the introduction of human immunodeficiency virus (HIV) infection into intravenous drug abusing populations, risk behaviors of 1,154 intravenous drug abusers (IVDAs) in four U.S. cities with low prevalence of IVDA/HIV infection (0.9-13.0%) were examined. Seropositive subjects (N = 54) were compared with demographically matched seronegative controls regarding drug use practices, homosexual contact, blood transfusions, risk behaviors while traveling or living in high prevalence areas, and acquaintance with persons with AIDS. With the exception of needle sharing with homosexual/bisexual males, no differences in risk behaviors were found between seropositive subjects and matched seronegatives. Seropositives were substantially more likely than matched seronegatives to report having shared a needle with a homosexual or bisexual male, suggesting that needle sharing between homosexual/bisexual IVDAs and heterosexual IVDAs may be an important means by which HIV is introduced among heterosexual IVDAs in low prevalence areas.

摘要

为探究人类免疫缺陷病毒(HIV)感染在静脉注射吸毒人群中的传播情况,对美国四个城市中1154名静脉注射吸毒者(IVDA)的危险行为进行了调查,这些城市的IVDA/HIV感染率较低(0.9%-13.0%)。将血清反应阳性者(N = 54)与人口统计学特征匹配的血清反应阴性对照者在吸毒习惯、同性恋接触、输血、在高感染率地区旅行或居住时的危险行为以及与艾滋病患者的相识情况等方面进行了比较。除了与同性恋/双性恋男性共用针头外,血清反应阳性者和匹配的血清反应阴性者在危险行为方面未发现差异。血清反应阳性者比匹配的血清反应阴性者更有可能报告曾与同性恋或双性恋男性共用针头,这表明同性恋/双性恋IVDA与异性恋IVDA之间共用针头可能是HIV在低感染率地区异性恋IVDA中传播的一个重要途径。

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