糖尿病和非糖尿病患者龈沟血的血糖仪评估：一项随机临床试验。
Glucometric assessment of gingival crevicular blood in diabetic and non-diabetic patients: A randomized clinical trial.
作者信息
Debnath Puja, Govila Vivek, Sharma Mona, Saini Ashish, Pandey Suraj
机构信息
Department of Periodontics and Implantology, BBD College of Dental Sciences, Lucknow, Uttar Pradesh, India.
Professor and Dean, Department of Periodontics and Implantology, BBD College of Dental Sciences, Lucknow, Uttar Pradesh, India.
出版信息
J Oral Biol Craniofac Res. 2015 Jan-Apr;5(1):2-6. doi: 10.1016/j.jobcr.2014.12.004. Epub 2015 Feb 23.
BACKGROUND
Diabetes mellitus is one of the most incessant metabolic afflictions with high prevalence rate in Indians. Diagnosis of diabetics in the initial stage helps to prevent its long term complications that are responsible for high morbidity and mortality. The aim of the present study was to assess whether glucometric analysis using Gingival Crevicular Blood (GCB) can be used for screening of diabetic patients in dental chair.
MATERIALS AND METHODS
Present study was a double blinded randomized controlled trial. A total of 50 patients, 25 diabetic and 25 non-diabetic with chronic periodontitis were enrolled in the study. Blood oozing from the gingival crevices after periodontal pocket probing of anterior teeth and Finger Prick Blood (FPB) was taken and analysed by glucometer.
RESULT
Mean ± S.D was 195.84 ± 27.19 and 138.78 ± 29.95 for GCB and FPB respectively in diabetic group. For non-diabetic group Mean ± S.D was 103.84 ± 12.56 and 84.36 ± 10.36 respectively for GCB and FPB. A Karl Pearson correlation coefficient value of r = +0.735 for diabetic and r = +0.802 for non-diabetic group comparing GCB and FPB.
CONCLUSION
GCB cannot be used for screening blood glucose during periodontal examination.
背景
糖尿病是印度患病率极高的最常见代谢性疾病之一。在糖尿病初期进行诊断有助于预防其导致高发病率和高死亡率的长期并发症。本研究的目的是评估使用龈沟血（GCB）进行血糖仪分析是否可用于在牙科治疗椅上筛查糖尿病患者。
材料与方法
本研究为双盲随机对照试验。共有50名患者参与研究，其中25名糖尿病患者和25名患有慢性牙周炎的非糖尿病患者。在前牙牙周袋探查后从龈沟渗出的血液以及指尖血（FPB）被采集并通过血糖仪进行分析。
结果
糖尿病组中，GCB和FPB的均值±标准差分别为195.84±27.19和138.78±29.95。非糖尿病组中，GCB和FPB的均值±标准差分别为103.84±12.56和84.36±10.36。比较GCB和FPB，糖尿病组的卡尔·皮尔逊相关系数值r = +0.735，非糖尿病组的r = +0.802。
结论
在牙周检查期间，GCB不能用于筛查血糖。
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