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黄斑脱离性孔源性视网膜脱离术后的视物变形:与视觉功能、视觉相关生活质量及光学相干断层扫描结果的关联

Postoperative metamorphopsia in macula-off rhegmatogenous retinal detachment: associations with visual function, vision related quality of life, and optical coherence tomography findings.

作者信息

van de Put Mathijs A J, Vehof Jelle, Hooymans Johanna M M, Los Leonoor I

机构信息

Department of Ophthalmology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

Department of Ophthalmology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands; Department of Twin Research & Genetic Epidemiology, King's College London, St. Thomas' Hospital, London, United Kingdom.

出版信息

PLoS One. 2015 Apr 8;10(4):e0120543. doi: 10.1371/journal.pone.0120543. eCollection 2015.

Abstract

PURPOSE

To evaluate postoperative metamorphopsia in macula-off rhegmatogenous retinal detachment (RRD) and its association with visual function, vision related quality of life, and optical coherence tomography (OCT) findings.

METHODS

45 patients with primary macula-off RRD were included. At 12 months postoperatively, data on metamorphopsia using sine amsler charts (SAC), best corrected visual acuity (BCVA), letter contrast sensitivity, color vision (saturated and desaturated color confusion indexes), critical print size, reading acuity, the 25-item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25), and OCT, were obtained.

RESULTS

Metamorphopsia was present in 39 patients (88.6%), with most of them (n = 35, 77.8%) showing only mild metamorphopsia (SAC score = 1). Patients with metamorphopsia had significantly worse postoperative BCVA (p = 0.02), critical print size (p<0.0005), and reading acuity (p = 0.001) compared to patients without metamorphopsia. Other visual function outcomes and NEI-VFQ-25 overall composite score were all also somewhat lower in patients with metamorphopsia, but this did not reach statistical significance. No association with OCT findings was present.

CONCLUSION

The prevalence of postoperative metamorphopsia in macula-off RRD patients is high, however, the degree of metamorphopsia is relatively low. When metamorphopsia is present, visual functions seem to be compromised, while vision related quality of life is only mildly affected.

摘要

目的

评估黄斑脱离性孔源性视网膜脱离(RRD)术后的视物变形及其与视功能、视觉相关生活质量和光学相干断层扫描(OCT)结果的关联。

方法

纳入45例原发性黄斑脱离性RRD患者。术后12个月时,获取使用正弦阿姆斯勒表(SAC)测量的视物变形数据、最佳矫正视力(BCVA)、字母对比敏感度、色觉(饱和及不饱和颜色混淆指数)、临界印刷字体大小、阅读视力、25项美国国立眼科研究所视觉功能问卷(NEI-VFQ-25)以及OCT数据。

结果

39例患者(88.6%)存在视物变形,其中大多数(n = 35,77.8%)仅表现为轻度视物变形(SAC评分为1)。与无视物变形的患者相比,有视物变形的患者术后BCVA显著更差(p = 0.02)、临界印刷字体大小显著更小(p<0.0005)、阅读视力显著更低(p = 0.001)。有视物变形的患者的其他视功能结果和NEI-VFQ-25总体综合评分也均略低,但未达到统计学显著性。与OCT结果无关联。

结论

黄斑脱离性RRD患者术后视物变形的发生率较高,然而,视物变形的程度相对较低。当存在视物变形时,视功能似乎受到损害,而视觉相关生活质量仅受到轻度影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/658e/4390319/4d5c1d488f16/pone.0120543.g001.jpg

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