Sánchez Álvarez C, Zabarte Martínez de Aguirre M, Bordejé Laguna L
Hospital General Universitario Reina Sofía, Murcia, España.
Med Intensiva. 2011 Nov;35 Suppl 1:42-7. doi: 10.1016/S0210-5691(11)70009-2.
Gastrointestinal surgery and critical illness place tremendous stress on the body, resulting in a series of metabolic changes that may lead to severe malnutrition, which in turn can increase postsurgical complications and morbidity and mortality and prolong the hospital length of stay. In these patients, parenteral nutrition is the most widely used form of nutritional support, but administration of enteral nutrition early in the postoperative period is effective and well tolerated, reducing infectious complications, improving wound healing and reducing length of hospital stay. Calorie-protein requirements do not differ from those in other critically-ill patients and depend on the patient's underlying process and degree of metabolic stress. In patients intolerant to enteral nutrition, especially if the intolerance is due to increased gastric residual volume, prokinetic agents can be used to optimize calorie intake. When proximal sutures are used, tubes allowing early jejunal feeding should be used. Pharmaconutrition is indicated in these patients, who benefit from enteral administration of arginine, omega 3 and RNA, as well as parenteral glutamine supplementation. Parenteral nutrition should be started in patients with absolute contraindication for use of the gastrointestinal tract or as complementary nutrition if adequate energy intake is not achieved through the enteral route.
胃肠手术和危重症会给身体带来巨大压力,导致一系列代谢变化,可能引发严重营养不良,进而增加术后并发症、发病率和死亡率,并延长住院时间。在这些患者中,肠外营养是最广泛使用的营养支持形式,但术后早期给予肠内营养是有效的,且耐受性良好,可减少感染性并发症,促进伤口愈合并缩短住院时间。热量 - 蛋白质需求与其他危重症患者并无差异,取决于患者的基础病情和代谢应激程度。对于不耐受肠内营养的患者,尤其是不耐受是由于胃残余量增加所致时,可使用促动力药物来优化热量摄入。当使用近端缝合时,应使用允许早期空肠喂养的导管。这些患者适合使用药理营养,他们可从肠内给予精氨酸、ω-3脂肪酸和RNA以及肠外补充谷氨酰胺中获益。对于存在使用胃肠道的绝对禁忌证的患者,或如果通过肠内途径无法实现足够的能量摄入时作为补充营养,应开始给予肠外营养。