Maoz-Segal Ramit, Agmon-Levin Nancy, Israeli Eitan, Shoenfeld Yehuda
Harefuah. 2015 Feb;154(2):129-32, 134.
The entity 'sick building syndrome' is poorly defined and comprises of a set of symptoms resulting from environmental exposure to a work or a living environment. The symptoms are mainly "allergic"-like and include nasal, eye, and mucous membrane irritation, dry skin as well as respiratory symptoms and general symptoms such as fatigue, lethargy, headaches and fever. The Autoimmune [Auto-inflammatory] Syndrome Induced by Adjuvants (ASIA) is a wider term which describes the role of various environmental factors in the pathogenesis of immune mediated diseases. Factors entailing an immune adjuvant activity such as infectious agents, silicone, aluminium salts and others were found in association with defined and non-defined immune mediated diseases. The sick building syndrome and ASIA share a similar complex of signs and symptoms and probably the same immunological mechanisms which further support a common denominator.
“病态建筑综合征”这一概念定义尚不明确，它包含一系列因暴露于工作或生活环境中的环境因素而产生的症状。这些症状主要类似“过敏”症状，包括鼻腔、眼睛和黏膜刺激、皮肤干燥以及呼吸道症状和诸如疲劳、无精打采、头痛和发烧等全身症状。佐剂诱导的自身免疫[自身炎症]综合征（ASIA）是一个更宽泛的术语，它描述了各种环境因素在免疫介导疾病发病机制中的作用。已发现具有免疫佐剂活性的因素，如传染因子、硅酮、铝盐等，与明确的和不明确的免疫介导疾病有关。病态建筑综合征和ASIA有着相似的体征和症状组合，可能还有相同的免疫机制，这进一步支持了它们存在共同特性的观点。
