组织转谷氨酰胺酶IgA抗体作为肠易激综合征患者样本中乳糜泻标志物的存在情况。

Presence of tissue transglutaminase IgA antibody as a celiac disease marker in a sample of patients with irritable bowel syndrome.

作者信息

Zamot Alberto L, Torres Esther A, González Henry, Marcial Manuel A

出版信息

P R Health Sci J. 2015 Mar;34(1):38-9.

Abstract

Recent medical literature agrees that celiac disease (CD) is much more prevalent in western civilization than it was thought to be in the past. Given the potential complications and consequences of untreated CD, screening programs have been considered. Symptoms of celiac disease may resemble those of Irritable Bowel Syndrome. A group of patients with IBS was screened for CE using the Tissue Transglutaminase Antibody IgA serum test. A total of 18 patients were screened. All of our patients tested negative for TTG IgA. This finding may indicate that the prevalence of CD may be low in our population. Further population studies are needed to confirm our finding.

摘要

近期医学文献一致认为，乳糜泻（CD）在西方文明中的发病率比过去认为的要高得多。鉴于未经治疗的乳糜泻可能产生的并发症和后果，人们已考虑开展筛查项目。乳糜泻的症状可能与肠易激综合征相似。一组肠易激综合征患者通过组织转谷氨酰胺酶抗体IgA血清检测进行了乳糜泻筛查。总共筛查了18名患者。我们所有患者的TTG IgA检测均为阴性。这一发现可能表明我们人群中乳糜泻的发病率可能较低。需要进一步的人群研究来证实我们的发现。