Henricson Cecilia, Lidestam Björn, Lyxell Björn, Möller Claes
Swedish Institute for Disability Research (SIDR) Linköping, Sweden ; Linnaeus Centre for Research on Hearing and Deafness (HEAD) Linköping, Sweden ; Department of Behavioral Sciences and Learning, Linköping University Linköping, Sweden.
Linnaeus Centre for Research on Hearing and Deafness (HEAD) Linköping, Sweden ; Department of Behavioral Sciences and Learning, Linköping University Linköping, Sweden.
Front Psychol. 2015 Mar 25;6:326. doi: 10.3389/fpsyg.2015.00326. eCollection 2015.
To investigate working memory (WM), phonological skills, lexical skills, and reading comprehension in adults with Usher syndrome type 2 (USH2).
The participants performed tests of phonological processing, lexical access, WM, and reading comprehension. The design of the test situation and tests was specifically considered for use with persons with low vision in combination with hearing impairment. The performance of the group with USH2 on the different cognitive measures was compared to that of a matched control group with normal hearing and vision (NVH).
Thirteen participants with USH2 aged 21-60 years and a control group of 10 individuals with NVH, matched on age and level of education.
The group with USH2 displayed significantly lower performance on tests of phonological processing, and on measures requiring both fast visual judgment and phonological processing. There was a larger variation in performance among the individuals with USH2 than in the matched control group.
The performance of the group with USH2 indicated similar problems with phonological processing skills and phonological WM as in individuals with long-term hearing loss. The group with USH2 also had significantly longer reaction times, indicating that processing of visual stimuli is difficult due to the visual impairment. These findings point toward the difficulties in accessing information that persons with USH2 experience, and could be part of the explanation of why individuals with USH2 report high levels of fatigue and feelings of stress (Wahlqvist et al., 2013).
研究2型Usher综合征（USH2）成人患者的工作记忆（WM）、语音技能、词汇技能和阅读理解能力。
参与者进行了语音处理、词汇通达、工作记忆和阅读理解测试。测试情境和测试的设计是专门考虑用于视力低下合并听力障碍的人群。将USH2组在不同认知测量上的表现与听力和视力正常的匹配对照组（NVH）进行比较。
13名年龄在21 - 60岁之间的USH2患者和一个由10名年龄和教育水平匹配的NVH个体组成的对照组。
USH2组在语音处理测试以及需要快速视觉判断和语音处理的测量中表现明显较差。USH2个体之间的表现差异比匹配对照组更大。
USH2组的表现表明，其在语音处理技能和语音工作记忆方面存在与长期听力损失个体类似的问题。USH2组的反应时间也明显更长，表明由于视力障碍，视觉刺激的处理存在困难。这些发现指出了USH2患者在获取信息方面所经历的困难，这可能是USH2患者报告高水平疲劳和压力感的部分原因（瓦尔奎斯特等人，2013年）。
