Toporova S G
Kardiologiia. 1989 Aug;29(8):80-3.
Life-time microscopy showed possible direct effects of obsidan on lymph vessels and flow in the experiment. With local application of the drug there was a short-term constriction, higher frequencies and lower amplitudes of lymphangionic pulsation; during its intramuscular injection, sustained dilator effects, two-phase shifts in the frequency and limitation of pulse amplitude were seen. With the two routes of obsidan administration heterogenous, unpersistent changes in the linear velocity of lymph flow were observed.
实时显微镜观察显示,在实验中黑曜石对淋巴管和淋巴液流动可能有直接影响。局部应用该药物时,淋巴管出现短期收缩,淋巴管搏动频率升高而幅度降低;肌肉注射时,则出现持续的扩张效应,频率出现两阶段变化且脉冲幅度受限。通过这两种黑曜石给药途径,观察到淋巴液线性流速出现异质性、非持续性变化。