McHale N G, Roddie I C
J Physiol. 1983 Aug;341:517-26. doi: 10.1113/jphysiol.1983.sp014821.
Pressure fluctuations and lymph flow were measured in popliteal, prefemoral and mesenteric efferent lymphatic vessels in conscious sheep. Intravenous adrenaline infusion increased frequency of lymphatic contraction and lymph flow in all three vessels. In the case of the prefemoral vessels flow remained high after the infusion had stopped. Intravenous noradrenaline infusion also increased frequency of contraction and lymph flow in all three vessels but prefemoral flow was depressed after the infusion had stopped. Lymphatic frequency of contraction and lymph flow increased when the animals were started. Anaesthetizing the animals with pentobarbitone did not abolish lymphatic contractions, nor did it prevent the response to adrenaline and noradrenaline infusion. The most obvious interpretation of these results is that adrenaline and noradrenaline act by increasing frequency and force of pumping of lymphatic vessels.
在清醒绵羊的腘、股前和肠系膜输出淋巴管中测量了压力波动和淋巴流量。静脉注射肾上腺素可增加所有这三条淋巴管的收缩频率和淋巴流量。就股前淋巴管而言，注射停止后流量仍保持较高水平。静脉注射去甲肾上腺素也增加了所有这三条淋巴管的收缩频率和淋巴流量，但注射停止后股前淋巴管的流量降低。动物开始活动时，淋巴管的收缩频率和淋巴流量增加。用戊巴比妥麻醉动物并没有消除淋巴管的收缩，也没有阻止对肾上腺素和去甲肾上腺素注射的反应。对这些结果最明显的解释是，肾上腺素和去甲肾上腺素通过增加淋巴管的泵血频率和力量来发挥作用。
