Steiman R, Bartoli M H, Seigle-Murandi F, Boitard M, Beriel H, Villard J
Groupe Métabolites d'origine fongique, UFR de Pharmacie, Meylan, France.
Microbiologica. 1989 Oct;12(4):307-16.
The ability of 211 strains of Micromycetes to produce antibiotic, antifungal and antitumoral compounds has been investigated in vitro using test strains and P 388 leukemia cells. Cytotoxicity was determined on Vero cells. Convenient activities were obtained depending on the taxonomic group. Finally, 17 strains of Micromycetes were selected for their antibacterial or antifungal activities and 12 for their antitumoral properties. Investigations are in progress concerning these activities.
利用测试菌株和P 388白血病细胞在体外研究了211株微真菌产生抗生素、抗真菌和抗肿瘤化合物的能力。在Vero细胞上测定细胞毒性。根据分类学类别获得了相应的活性。最后，选择了17株具有抗菌或抗真菌活性的微真菌菌株和12株具有抗肿瘤特性的菌株。关于这些活性的研究正在进行中。
