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来自盾叶薯蓣内生真菌Dzf12的螺双萘及其抗菌活性。

Spirobisnaphthalenes from the endophytic fungus Dzf12 of Dioscorea zingiberensis and their antimicrobial activities.

作者信息

Cai Xiaoyue, Shan Tijiang, Li Peiqin, Huang Yongfu, Xu Lijian, Zhou Ligang, Wang Mingan, Jiang Weibo

机构信息

College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China.

出版信息

Nat Prod Commun. 2009 Nov;4(11):1469-72.

Abstract

Five spirobisnaphthalenes, namely palmarumycin CP17 (1), diepoxin kappa (2), diepoxin eta (3), diepoxin xi (4), and diepoxin gamma (5), were isolated from the endophytic fungus Dzf12 associated with the medicinal plant Dioscorea zingiberensis C. H. Wright. Their structures were identified by physicochemical and spectrometric analysis. Among these spirobisnaphthalenes, 2 was found to have antibacterial activity, and the mixture of 3 and 4 was detected to have both antibacterial and antifungal activities.

摘要

从与药用植物盾叶薯蓣(Dioscorea zingiberensis C. H. Wright)相关的内生真菌Dzf12中分离出了五种螺二萘,即棕榈霉素CP17(1)、二环氧κ(2)、二环氧η(3)、二环氧ξ(4)和二环氧γ(5)。通过物理化学和光谱分析确定了它们的结构。在这些螺二萘中,发现2具有抗菌活性,并且检测到3和4的混合物具有抗菌和抗真菌活性。

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