Meadows A T, McKee L, Kazak A E
Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia.
Med Pediatr Oncol. 1989;17(6):466-70. doi: 10.1002/mpo.2950170523.
The majority of childhood cancer patients now can expect to survive into early adulthood, cured of their cancer. Current adult survivors are a diverse group in terms of diagnosis, age at diagnosis, and types of treatment. It is estimated that by 1990, 1 in every 1,000 twenty-year-olds will have had cancer, making it important to describe the long-term psychosocial adjustment of this population. Patients who were diagnosed between 1948 and 1975 while less than 16 years of age, who were currently 18 years or older, had been off therapy for at least 5 years, and had no known brain damage were eligible for this survey and were identified through the tumor registry at the Children's Hospital of Philadelphia (CHP). Initially, the parents were contacted by letter. Ninety-five (57%) of the 167 eligible patients participated in a telephone interview, which covered educational achievement, occupational status, interpersonal relationships, marital status, pregnancies, employee benefits and insurance, and medical and health behaviors. Respondents were not different from nonrespondents in terms of sex, year of diagnosis, age at diagnosis, diagnoses, stage of illness, or type of treatments. There were no differences in terms of education, marital status, fertility issues, or occupational status by diagnosis group, age at diagnosis, or treatments. The patients were compared to siblings over 18 years of age in terms of education and marital status. No significant differences in sex distribution or years of education between patients and siblings were found. The siblings were, as a group, older than the patients and were more likely to be married. In general, these patients were functioning normally, but there are many unexplored areas of interpersonal relationships and productivity that need further study before conclusions regarding psychosocial adjustment of childhood cancer survivors can be drawn.
现在，大多数儿童癌症患者有望存活至成年早期，并治愈癌症。目前的成年幸存者在诊断、诊断年龄和治疗类型方面是一个多样化的群体。据估计，到1990年，每1000名20岁的年轻人中就有1人患过癌症，因此描述这一人群的长期心理社会适应情况很重要。在1948年至1975年期间被诊断出患有癌症、当时年龄小于16岁、目前年龄在18岁及以上、已停止治疗至少5年且无已知脑损伤的患者有资格参加这项调查，并通过费城儿童医院（CHP）的肿瘤登记处进行识别。最初，通过信件联系家长。167名符合条件的患者中有95名（57%）参加了电话访谈，访谈内容包括教育成就、职业状况、人际关系、婚姻状况、怀孕情况、员工福利和保险以及医疗和健康行为。在性别、诊断年份、诊断年龄、诊断结果、疾病阶段或治疗类型方面，受访者与未受访者没有差异。在教育程度、婚姻状况、生育问题或职业状况方面，按诊断组、诊断年龄或治疗方法划分没有差异。将这些患者在教育程度和婚姻状况方面与18岁以上的兄弟姐妹进行比较。在患者和兄弟姐妹之间，未发现性别分布或教育年限有显著差异。作为一个群体，兄弟姐妹比患者年龄大，结婚的可能性也更大。总体而言，这些患者功能正常，但在人际关系和生产力方面有许多未探索的领域，在得出关于儿童癌症幸存者心理社会适应的结论之前，需要进一步研究。
