Van der Veken Dominique, De Haes Petra, Hauben Esther, Teughels Wim, Lambrechts Paul
Department of Oral Health Sciences, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium.
Department of Dermatology, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 May;119(5):e257-64. doi: 10.1016/j.oooo.2015.02.002. Epub 2015 Feb 14.
Morphea is an inflammatory disorder of the skin and underlying tissues characterized by an overabundance of collagen leading to fibrosis. The prevalence of this disease is estimated at around 0.4-2.7/100,000 people. When the process occurs in the gingival tissues, it induces traction, which can cause gingival recession. A 19-year-old woman was referred to the clinic for a progressive recession on teeth 11 and 12. A pale, atrophic, linear region extending from her nose to her upper lip on the right-hand side of her face was diagnosed as morphea en coup de sabre. Cone beam computed tomography, quantitative polymerase chain reaction and histologic evaluation were used to assess the pathology. Treatment with methotrexate was conducted. After 12 months, no progression of the recession could be observed.
硬斑病是一种皮肤及皮下组织的炎症性疾病，其特征是胶原蛋白过多导致纤维化。这种疾病的患病率估计约为每10万人中有0.4 - 2.7人。当病变过程发生在牙龈组织时，会引起牵拉，进而导致牙龈退缩。一名19岁女性因11号和12号牙的渐进性退缩被转诊至诊所。在她面部右侧从鼻子延伸至上唇的一个苍白、萎缩的线性区域被诊断为剑伤性硬斑病。采用锥形束计算机断层扫描、定量聚合酶链反应和组织学评估来评估病理情况。进行了甲氨蝶呤治疗。12个月后，未观察到退缩情况进展。
