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硬斑病累及口腔黏膜并伴有单侧痣样毛细血管扩张作为硬斑病的早期表现:一例病例报告及文献复习

Morphea with Oral Mucosa Involvement and Unilateral Nevoid Telangiectasia as an Early Presentation of Morphea: A Case Report and Review of the Literature.

作者信息

Hirt Penelope, Paul Suchismita, Phuthongkam Weena, Schachner Lawrence

机构信息

All authors are with the Department of Dermatology and Cutaneous Surgery at the University of Miami, Miller School of Medicine in Miami, Florida.

Dr. Phuthongkam is also with the Department of Pediatrics at the Faculty of Medicine Vajira Hospital at Navamindradhiraj University in Bangkok, Thailand.

出版信息

J Clin Aesthet Dermatol. 2020 Jan;13(1):38-40. Epub 2020 Jan 1.

Abstract

Oral mucosal involvement in patients with morphea is quite rare. Unilateral nevoid telangiectasia is a rare vascular dermatosis characterized by unilateral telangiectasia distributed in a dermatomal pattern, especially on the upper trunk and extremities. We describe a case of a 10-year-old female patient that presents with morphea on her left chin and upper lip extending to the inner oral mucosa as well as a unilateral nevoid telangiectasia on her left cheek as an early presentation of localized scleroderma. This case is significant as it demonstrates a striking clinical presentation of morphea and an interesting early presentation of morphea as a unilateral nevoid telangiectasia that improved after treatment with oral methotrexate and prednisone.

摘要

硬斑病患者出现口腔黏膜受累的情况相当罕见。单侧痣样毛细血管扩张症是一种罕见的血管性皮肤病,其特征为单侧毛细血管扩张呈皮节分布,尤其见于上躯干和四肢。我们报告一例10岁女性患者,其左侧下巴和上唇出现硬斑病,并延伸至口腔内侧黏膜,同时左侧脸颊有单侧痣样毛细血管扩张症,这是局限性硬皮病的早期表现。该病例意义重大,因为它展示了硬斑病显著的临床表现,以及硬斑病作为单侧痣样毛细血管扩张症这一有趣的早期表现,经口服甲氨蝶呤和泼尼松治疗后病情有所改善。

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本文引用的文献

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Morphea "en coup de sabre": An unusual oral presentation.线状硬皮病:一种不寻常的口腔表现。
J Clin Exp Dent. 2017 Feb 1;9(2):e315-e318. doi: 10.4317/jced.53151. eCollection 2017 Feb.
2
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J Med Case Rep. 2016 Oct 24;10(1):297. doi: 10.1186/s13256-016-1086-1.
3
A rare cause of gingival recession: morphea with intra-oral involvement.牙龈退缩的罕见原因:硬斑病伴口腔内受累。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 May;119(5):e257-64. doi: 10.1016/j.oooo.2015.02.002. Epub 2015 Feb 14.
4
Linear scleroderma en coup de sabre including abnormal dental development.线性硬皮病之剑伤型,包括牙齿发育异常。
Eur Arch Paediatr Dent. 2015 Apr;16(2):227-31. doi: 10.1007/s40368-014-0148-6. Epub 2014 Oct 30.
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Scleroderma in children: an update.儿童硬皮病:最新进展。
Curr Opin Rheumatol. 2013 Sep;25(5):643-50. doi: 10.1097/BOR.0b013e3283641f61.
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Unilateral nevoid telangiectasia--report of two cases.单侧痣样毛细血管扩张症——两例报告。
Int J Dermatol. 2014 Jan;53(1):e32-3. doi: 10.1111/j.1365-4632.2011.05457.x. Epub 2013 Mar 3.
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Odontostomatologic involvement in juvenile localised scleroderma of the face.面部青少年局限性硬皮病的口腔颌面受累情况。
J Paediatr Child Health. 2012 Jul;48(7):572-6. doi: 10.1111/j.1440-1754.2012.02435.x. Epub 2012 Mar 12.
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Early localized morphea mimicking an acquired port-wine stain.早期局限性硬斑病酷似获得性葡萄酒色斑。
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