Khurana S, Hallur V, Goyal M K, Sehgal R, Radotra B D
Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Med Microbiol. 2015 Apr-Jun;33(2):298-300. doi: 10.4103/0255-0857.154887.
We report two cases of fatal chronic meningoencephalitis caused by Balamuthia mandrillaris in immunocompetent men. Diagnosis of amoebic meningoencephalitis was made ante-mortem in one case and postmortem in another by histopathological examination and confirmed by demonstration of B. mandrillaris deoxyribonucleic acid (DNA) by polymerase chain reaction (PCR).
我们报告了两例由曼氏巴通体引起的免疫功能正常男性致命性慢性脑膜脑炎病例。其中一例通过组织病理学检查在生前诊断为阿米巴脑膜脑炎,另一例在死后诊断,通过聚合酶链反应(PCR)检测到曼氏巴通体脱氧核糖核酸(DNA)得以确诊。