Crittenden Ben M, Mitchell Daniel J, Duncan John
Medical Research Council Cognition and Brain Sciences Unit, Cambridge, United Kingdom.
University of Cambridge, Cambridge, United Kingdom.
Elife. 2015 Apr 13;4:e06481. doi: 10.7554/eLife.06481.
In the human brain, a default mode or task-negative network shows reduced activity during many cognitive tasks and is often associated with internally-directed processes, such as mind wandering and thoughts about the self. In contrast to this task-negative pattern, we show increased activity during a large and demanding switch in task set. Furthermore, we employ multivoxel pattern analysis and find that regions of interest within default mode network are encoding task-relevant information during task performance. Activity in this network may be driven by major revisions of cognitive context, whether internally or externally focused.
在人类大脑中，一种默认模式或任务负性网络在许多认知任务期间表现出活动减少，并且通常与内部导向的过程相关联，比如思绪游荡和关于自我的思考。与这种任务负性模式相反，我们发现在任务集发生重大且要求较高的切换期间活动增加。此外，我们采用多体素模式分析，发现在任务执行期间默认模式网络内的感兴趣区域正在编码与任务相关的信息。该网络中的活动可能由认知背景的重大调整所驱动，无论这种调整是聚焦于内部还是外部。
