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管理耐甲氧西林金黄色葡萄球菌引起的皮肤软组织感染和医院获得性肺炎:2014 年随访调查。

Managing skin and soft-tissue infection and nosocomial pneumonia caused by MRSA: a 2014 follow-up survey.

机构信息

Department of Microbiology and Communicable Diseases, Royal Hampshire County Hospital, Romsey Road, Winchester, Hampshire SO22 5DG, UK.

Department of Clinical Microbiology, University Hospital for Infectious Diseases, Zagreb, Croatia.

出版信息

Int J Antimicrob Agents. 2015 Apr 24;45 Suppl 1:S1-14. doi: 10.1016/S0924-8579(15)30002-9.

Abstract

As a follow-up to our 2009 survey, in order to explore opinion and practice on the epidemiology and management of meticillin-resistant Staphylococcus aureus (MRSA) in Europe, we conducted a second survey to elicit current opinions on this topic, particularly around antibiotic choice, dose, duration and route of administration. We also aimed to further understand how the management of MRSA has evolved in Europe during the past 5 years. Members of an expert panel of infectious diseases specialists convened in London (UK) in January 2014 to identify and discuss key issues in the management of MRSA. Following this meeting, a survey was developed comprising 36 questions covering a wide range of topics on MRSA complicated skin and soft-tissue infection and nosocomial pneumonia management. The survey instrument, a web-based questionnaire, was sent to the International Society of Chemotherapy for distribution to registered European infection societies and their members. This article reports the survey results from the European respondents. At the time of the original survey, the epidemiology of MRSA varied significantly across Europe and there were differing views on best practice. The current findings suggest that the epidemiology of healthcare-associated MRSA in Europe is, if anything, even more polarised, whilst community-acquired MRSA has become much more common. However, there now appears to be a much greater knowledge of current treatment/management options, and antimicrobial stewardship has moved forward considerably in the 5 years since the last survey.

摘要

作为我们 2009 年调查的后续行动,为了探索欧洲耐甲氧西林金黄色葡萄球菌(MRSA)的流行病学和管理方面的意见和实践,我们进行了第二次调查,以了解关于这一主题的当前意见,特别是在抗生素选择、剂量、持续时间和给药途径方面。我们还旨在进一步了解在过去 5 年中,欧洲在 MRSA 管理方面的演变。2014 年 1 月,传染病专家组成的专家小组在伦敦(英国)开会,以确定和讨论 MRSA 管理方面的关键问题。会后,制定了一项涵盖 36 个问题的调查,涵盖了 MRSA 复杂性皮肤和软组织感染以及医院获得性肺炎管理的广泛主题。调查工具是一个基于网络的问卷,由国际化疗学会分发给注册的欧洲感染学会及其成员。本文报告了来自欧洲受访者的调查结果。在最初的调查时,欧洲的 MRSA 流行病学差异很大,最佳实践也存在不同意见。目前的研究结果表明,欧洲医疗保健相关 MRSA 的流行病学甚至更加两极化,而社区获得性 MRSA 则变得更加普遍。然而,现在似乎对当前治疗/管理选择有了更多的了解,并且抗菌药物管理在过去 5 年中取得了很大进展。

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