加利福尼亚州因高水平耐药导致阿奇霉素2.0克治疗淋菌性尿道炎失败。
Failure of azithromycin 2.0 g in the treatment of gonococcal urethritis caused by high-level resistance in California.
作者信息
Gose Severin O, Soge Olusegun O, Beebe James L, Nguyen Duylinh, Stoltey Juliet E, Bauer Heidi M
机构信息
From the *San Francisco Public Health Laboratory, San Francisco Department of Public Health, San Francisco, CA; †Neisseria Reference Laboratory, Department of Global Health and Center for AIDS and STD, University of Washington, Seattle, WA; ‡Public Health Laboratory, San Luis Obispo Department of Public Health, San Luis Obispo, CA; and §Sexually Transmitted Disease (STD) Control Branch, Division of Communicable Disease Control (DCDC), Center for Infectious Diseases (CID), California Department of Public Health (CDPH), Richmond, CA.
出版信息
Sex Transm Dis. 2015 May;42(5):279-80. doi: 10.1097/OLQ.0000000000000265.
Abstract
We report a treatment failure to azithromycin 2.0 g caused by a urethral Neisseria gonorrhoeae isolate with high-level azithromycin resistance in California. This report describes the epidemiological case investigation and phenotypic and genetic characterization of the treatment failure isolate.
摘要
我们报告了加利福尼亚州一起由对阿奇霉素具有高水平耐药性的尿道淋病奈瑟菌分离株导致的阿奇霉素2.0克治疗失败病例。本报告描述了该治疗失败分离株的流行病学病例调查以及表型和基因特征。
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2
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3
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4
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5
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Sex Transm Infect. 2013 Dec;89 Suppl 4:iv47-51. doi: 10.1136/sextrans-2013-051020.
6
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Sex Transm Dis. 2012 Nov;39(11):877-9. doi: 10.1097/OLQ.0b013e3182685d2b.
7
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