北卡罗来纳州首例高水平耐阿奇霉素淋病奈瑟菌感染病例。
First Case of High-Level Azithromycin-Resistant Neisseria gonorrhoeae in North Carolina.
机构信息
From the Department of Pathology, Wake Forest School of Medicine and Wake Forest Baptist Health, Winston-Salem, NC.
Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
出版信息
Sex Transm Dis. 2020 May;47(5):326-328. doi: 10.1097/OLQ.0000000000001149.
Abstract
We report on the first high-level azithromycin-resistant Neisseria gonorrhoeae isolate (minimum inhibitory concentration, ≥256 μg/mL) in North Carolina isolated from a pharyngeal swab of a 33-year-old HIV-negative man who has sex with men. In addition, the isolate was found to be susceptible to cefixime, ceftriaxone, and penicillin and resistant to tetracycline. By whole-genome sequencing, the strain was assigned as MLST ST9363, NG-MAST ST5035, and a novel NG-STAR sequence type, ST1993.
摘要
我们报告了北卡罗来纳州首例高水平阿奇霉素耐药淋病奈瑟菌分离株（最低抑菌浓度≥256μg/ml），该分离株从一名 33 岁的 HIV 阴性男性的咽拭子中分离得到，该男性与男性发生性行为。此外，该分离株对头孢克肟、头孢曲松和青霉素敏感，对四环素耐药。通过全基因组测序，该菌株被鉴定为 MLST ST9363、NG-MAST ST5035 和新型 NG-STAR 序列型 ST1993。
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