Graham Eleanor A M
Forensic Pathology Unit, University of Leicester, Robert Kilpatrick Building Leicester Royal Infirmary, LE2 7LX, Leicester, United Kingdom,
Forensic Sci Med Pathol. 2005 Dec;1(4):285-8. doi: 10.1385/FSMP:1:4:285.
DNA profile analysis is not a simple process. Stringent demands are placed on the accuracy and consistency of forensic evidence so that complex, robust, and reproducible guidelines are necessary to assist the analyst and ensure mistakes are eliminated before a final profile is reported. The guidelines used for forensic DNA profile interpretation are formulated by investigation and statistical evaluation of all aspects of the analytical procedure. All the resulting rules, formulas, and thresholds are perfectly suited to programming of "expert systems"-software programs that imitate the human expert in decision-based processes to formulate a conclusion. Expert systems in forensic DNA analysis will contribute greatly to this field by increasing analytical throughput. The net result of this will be an increase in the human resources available for the research and development of improved methodologies, to ensure that forensic DNA profiling continues to advance at its current impressive rate.
DNA 图谱分析并非一个简单的过程。对法医证据的准确性和一致性有着严格要求，因此需要复杂、稳健且可重复的指南来协助分析人员，并确保在报告最终图谱之前消除错误。用于法医 DNA 图谱解读的指南是通过对分析程序各个方面的调查和统计评估制定的。所有得出的规则、公式和阈值都非常适合“专家系统”的编程——即模仿人类专家在基于决策的过程中得出结论的软件程序。法医 DNA 分析中的专家系统将通过提高分析通量，为该领域做出巨大贡献。其最终结果将是增加可用于改进方法研发的人力资源，以确保法医 DNA 图谱分析继续以目前令人瞩目的速度发展。
