Graham Eleanor A M
Forensic Pathology Unit, University of Leicester Robert Kilpatrick Building Leicester Royal Infirmary, LE2 7LX, Leicester, United Kingdom,
Forensic Sci Med Pathol. 2005 Sep;1(3):221-3. doi: 10.1385/FSMP:1:3:221.
The techniques and laboratory processes involved in the production of DNA profiles for forensic applications are well developed, robust, and reliable. Unfortunately, they can now also be considered too slow and expensive to be able to match the ever-increasing demands placed upon them. The most rapid DNA profiling instrumentation in current usage are capillary electrophoresis (CE) systems. CE systems have greatly enhanced visualization and analysis throughput, but are still unable to keep up with current demand. However, developments in nanobiotechnology are allowing for the production of miniature systems to decrease the time and costs involved in profile production.
用于法医应用的DNA图谱制作所涉及的技术和实验室流程已经非常成熟、稳健且可靠。不幸的是,如今它们也被认为速度太慢且成本太高,无法满足不断增长的需求。当前使用的最快的DNA图谱分析仪器是毛细管电泳(CE)系统。CE系统极大地提高了可视化和分析通量,但仍无法跟上当前需求。然而,纳米生物技术的发展使得微型系统的生产成为可能,以减少图谱制作所涉及的时间和成本。