J Natl Compr Canc Netw. 2015 Apr;13(4):448-75. doi: 10.6004/jnccn.2015.0060.
Breast cancer is the most common malignancy in women in the United States and is second only to lung cancer as a cause of cancer death. The overall management of breast cancer includes the treatment of local disease with surgery, radiation therapy, or both, and the treatment of systemic disease with cytotoxic chemotherapy, endocrine therapy, biologic therapy, or combinations of these. This portion of the NCCN Guidelines discusses recommendations specific to the locoregional management of clinical stage I, II, and IIIA (T3N1M0) tumors.
乳腺癌是美国女性中最常见的恶性肿瘤，仅次于肺癌，是癌症死亡的第二大原因。乳腺癌的整体治疗包括手术、放疗或两者联合治疗局部疾病，以及细胞毒性化疗、内分泌治疗、生物治疗或这些方法的联合治疗全身疾病。NCCN 指南的这一部分讨论了针对临床 I 期、II 期和 IIIA（T3N1M0）肿瘤的局部区域管理的具体建议。
