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Brain circuits mediating the orexigenic action of peripheral ghrelin: narrow gates for a vast kingdom.

作者信息

Cabral Agustina, De Francesco Pablo N, Perello Mario

机构信息

Laboratory of Neurophysiology, Multidisciplinary Institute of Cell Biology [Argentine Research Council (CONICET) and Scientific Research Commission, Province of Buenos Aires (CIC-PBA)] , Buenos Aires , Argentina.

出版信息

Front Endocrinol (Lausanne). 2015 Mar 30;6:44. doi: 10.3389/fendo.2015.00044. eCollection 2015.

DOI:10.3389/fendo.2015.00044
PMID:25870587
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4378314/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a2c/4378314/ba34b6255100/fendo-06-00044-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a2c/4378314/ba34b6255100/fendo-06-00044-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a2c/4378314/ba34b6255100/fendo-06-00044-g001.jpg

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Mol Metab. 2014 Oct 24;4(1):15-24. doi: 10.1016/j.molmet.2014.10.003. eCollection 2015 Jan.
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Ghrelin signalling on food reward: a salient link between the gut and the mesolimbic system.胃饥饿素对食物奖赏的信号传导：肠道与中脑边缘系统之间的显著联系。
J Neuroendocrinol. 2015 Jun;27(6):424-34. doi: 10.1111/jne.12236.
3
Divergent neuronal circuitries underlying acute orexigenic effects of peripheral or central ghrelin: critical role of brain accessibility.
下丘脑室管膜细胞从脑脊液中内吞 ghrelin：分子机制和功能意义。
Mol Metab. 2024 Dec;90:102046. doi: 10.1016/j.molmet.2024.102046. Epub 2024 Oct 12.
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GHSR blockade, but not reduction of peripherally circulating ghrelin via β-adrenergic receptor antagonism, decreases binge-like alcohol drinking in mice.胃饥饿素受体阻断而非通过β-肾上腺素能受体拮抗作用降低外周循环胃饥饿素，可减少小鼠的暴饮样饮酒行为。
Mol Psychiatry. 2025 Mar;30(3):1047-1056. doi: 10.1038/s41380-024-02713-3. Epub 2024 Sep 5.
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Correlation analysis between the changes in plasma ghrelin level and weight loss after sleeve gastrectomy combined with fundoplication.胃袖状切除术联合胃底折叠术治疗后血浆 ghrelin 水平变化与体重减轻的相关性分析。
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